affectsCellType
P94935
predicate
Indicates that one entity produces an effect or change on a specific type of cell.
All labels observed (6)
| Label | Occurrences |
|---|---|
| actsOnCellType | 12 |
| affectsCellType canonical | 11 |
| targetCellType | 6 |
| cellTypeReprogrammed | 3 |
| effectOnBCells | 1 |
| effectOnCell | 1 |
Description generation (PDg)
The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.
Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning. # Instructions Focus on describing the relationship, not the entities themselves. # Response Format Begin the description with \' Indicates...\'
Input
Predicate: affectsCellType
Generated description
Indicates that one entity produces an effect or change on a specific type of cell.
Sample triples (34)
| Subject | Object |
|---|---|
| Dravet syndrome | GABAergic interneurons ⓘ |
| Riabni | B lymphocytes ⓘ |
| Yamanaka factors | convert differentiated cells to pluripotent state via predicate surface "effectOnCell" ⓘ |
| Yamanaka factors Oct3/4, Sox2, Klf4, and c-Myc | mouse fibroblasts via predicate surface "cellTypeReprogrammed" ⓘ |
| Yamanaka factors Oct3/4, Sox2, Klf4, and c-Myc | human fibroblasts via predicate surface "cellTypeReprogrammed" ⓘ |
| Yamanaka factors Oct3/4, Sox2, Klf4, and c-Myc | various somatic cell types via predicate surface "cellTypeReprogrammed" ⓘ |
| fingolimod | T lymphocytes ⓘ |
| fingolimod | B lymphocytes ⓘ |
| TDP-43 proteinopathy | motor neurons ⓘ |
| TDP-43 proteinopathy | cortical neurons ⓘ |
| TDP-43 proteinopathy | hippocampal neurons ⓘ |
| LOXO-305 | B lymphocytes via predicate surface "actsOnCellType" ⓘ |
| platelet-derived growth factor | fibroblasts via predicate surface "targetCellType" ⓘ |
| platelet-derived growth factor | smooth muscle cells via predicate surface "targetCellType" ⓘ |
| platelet-derived growth factor | glial cells via predicate surface "targetCellType" ⓘ |
| platelet-derived growth factor | mesenchymal cells via predicate surface "targetCellType" ⓘ |
| chronic lymphocytic leukemia |
B lymphocyte
ⓘ
linked to:
B lymphocytes
|
|
Vascular endothelial growth factor A
linked to:
vascular endothelial growth factor A
|
endothelial cell via predicate surface "actsOnCellType" ⓘ |
|
Vascular endothelial growth factor A
linked to:
vascular endothelial growth factor A
|
vascular smooth muscle cell (indirectly) via predicate surface "actsOnCellType" ⓘ |
| daratumumab | malignant plasma cell via predicate surface "targetCellType" ⓘ |
| daratumumab | normal plasma cell via predicate surface "targetCellType" ⓘ |
| isatuximab | malignant plasma cells via predicate surface "actsOnCellType" ⓘ |
| isatuximab | CD38-expressing hematologic tumor cells via predicate surface "actsOnCellType" ⓘ |
| mosunetuzumab | B lymphocytes via predicate surface "actsOnCellType" ⓘ |
| mosunetuzumab | T lymphocytes via predicate surface "actsOnCellType" ⓘ |
| mosunetuzumab | B-cell depletion via predicate surface "effectOnBCells" ⓘ |
| interleukin-4 | B cell via predicate surface "actsOnCellType" ⓘ |
| interleukin-4 | T helper cell via predicate surface "actsOnCellType" ⓘ |
| interleukin-4 | mast cell via predicate surface "actsOnCellType" ⓘ |
| interleukin-4 | eosinophil via predicate surface "actsOnCellType" ⓘ |
| interleukin-4 | macrophage via predicate surface "actsOnCellType" ⓘ |
| Krabbe disease | oligodendrocytes ⓘ |
| Krabbe disease | Schwann cells ⓘ |
| trapped neutrophil syndrome | neutrophil ⓘ |