Riabni
E261832
Riabni is a biosimilar monoclonal antibody to rituximab used in the treatment of certain cancers and autoimmune diseases.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Riabni canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T2371050 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Riabni Context triple: [Rituxan, hasBiosimilar, Riabni]
-
A.
Serebryanye Prudy
Serebryanye Prudy is a rural locality in Moscow Oblast, Russia, historically notable as the birthplace of Soviet Marshal Vasily Chuikov.
-
B.
Dzvina
Dzvina is the Belarusian name for the Daugava River, a major Eastern European river flowing through Russia, Belarus, and Latvia into the Baltic Sea.
-
C.
Urzhum
Urzhum is a small historic town in Kirov Oblast, Russia, known as the birthplace of prominent Soviet leader Sergei Kirov.
-
D.
Rissne
Rissne is a residential district and urban area in the Stockholm metropolitan region of Sweden, known for its mix of apartment housing and proximity to public transit.
-
E.
Yenakiieve
Yenakiieve is an industrial city in eastern Ukraine, historically known for its coal mining and metallurgical industries.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Riabni Target entity description: Riabni is a biosimilar monoclonal antibody to rituximab used in the treatment of certain cancers and autoimmune diseases.
-
A.
Serebryanye Prudy
Serebryanye Prudy is a rural locality in Moscow Oblast, Russia, historically notable as the birthplace of Soviet Marshal Vasily Chuikov.
-
B.
Dzvina
Dzvina is the Belarusian name for the Daugava River, a major Eastern European river flowing through Russia, Belarus, and Latvia into the Baltic Sea.
-
C.
Urzhum
Urzhum is a small historic town in Kirov Oblast, Russia, known as the birthplace of prominent Soviet leader Sergei Kirov.
-
D.
Rissne
Rissne is a residential district and urban area in the Stockholm metropolitan region of Sweden, known for its mix of apartment housing and proximity to public transit.
-
E.
Yenakiieve
Yenakiieve is an industrial city in eastern Ukraine, historically known for its coal mining and metallurgical industries.
- F. None of above. chosen
Statements (44)
| Predicate | Object |
|---|---|
| instanceOf |
biopharmaceutical drug
ⓘ
biosimilar medicine ⓘ monoclonal antibody ⓘ rituximab biosimilar ⓘ |
| affectsCellType | B lymphocytes ⓘ |
| hasActiveIngredient | rituximab-arrx ⓘ |
| hasATCClass | L01XC02 (rituximab class) ⓘ |
| hasBlackBoxWarning |
fatal infusion reactions
ⓘ
hepatitis B virus reactivation ⓘ progressive multifocal leukoencephalopathy ⓘ severe mucocutaneous reactions ⓘ |
| hasCommonAdverseEffect |
chills
ⓘ
fever ⓘ infections ⓘ infusion-related reactions ⓘ neutropenia ⓘ |
| hasDosageForm | solution for intravenous infusion ⓘ |
| hasDrugClass | CD20-directed cytolytic antibody ⓘ |
| hasGenericName | rituximab-arrx ⓘ |
| hasIndication |
chronic lymphocytic leukemia
ⓘ
diffuse large B-cell lymphoma ⓘ follicular lymphoma ⓘ granulomatosis with polyangiitis ⓘ
linked to:
Wegener's granulomatosis
microscopic polyangiitis ⓘ non-Hodgkin lymphoma ⓘ rheumatoid arthritis ⓘ |
| hasMechanismOfAction |
binds to CD20 on B lymphocytes
ⓘ
induces B-cell lysis ⓘ mediates antibody-dependent cellular cytotoxicity ⓘ mediates complement-dependent cytotoxicity ⓘ |
| hasMolecularType | chimeric monoclonal antibody ⓘ |
| hasRouteOfAdministration | intravenous infusion ⓘ |
| hasSpeciesOrigin | human-mouse chimeric ⓘ |
| hasTarget |
CD20 antigen
ⓘ
linked to:
CD20 protein
|
| hasTherapeuticArea |
immunology
ⓘ
oncology ⓘ rheumatology ⓘ |
| isAdministeredBy | healthcare professional ⓘ |
| isApprovedBy |
U.S. Food and Drug Administration
ⓘ
linked to:
Food and Drug Administration
|
| isBiosimilarTo |
Rituxan
ⓘ
rituximab ⓘ
linked to:
Rituxan
|
| isContraindicatedIn | patients with severe active infections ⓘ |
| isUsedFor |
treatment of certain autoimmune diseases
ⓘ
treatment of certain cancers ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Riabni Description of subject: Riabni is a biosimilar monoclonal antibody to rituximab used in the treatment of certain cancers and autoimmune diseases.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.