non-Hodgkin lymphoma
E99398
Non-Hodgkin lymphoma is a diverse group of blood cancers that originate in the lymphatic system from abnormal lymphocytes and can vary widely in aggressiveness and prognosis.
All labels observed (14)
How this entity was disambiguated
This entity first appeared as the object of triple T850660 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: non-Hodgkin lymphoma Context triple: [Jacqueline Kennedy Onassis, causeOfDeath, non-Hodgkin lymphoma]
-
A.
Hodgkin
Hodgkin is a surname most famously associated with Dorothy Hodgkin, the Nobel Prize–winning British chemist who advanced the field of X-ray crystallography.
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B.
Virchow's node
Virchow's node is an enlarged left supraclavicular lymph node that classically indicates metastatic spread from abdominal or thoracic malignancies, especially gastric cancer.
-
C.
SCLC
SCLC is a prominent American civil rights organization founded in 1957 that played a central role in the nonviolent struggle against racial segregation, led in part by Martin Luther King Jr.
-
D.
Rituxan
Rituxan is a monoclonal antibody drug (rituximab) widely used to treat certain blood cancers and autoimmune diseases by targeting the CD20 protein on B cells.
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E.
TNM
TNM is the IATA airport code for Teniente Rodolfo Marsh Martin Aerodrome, a Chilean airfield located on King George Island in Antarctica.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: non-Hodgkin lymphoma Target entity description: Non-Hodgkin lymphoma is a diverse group of blood cancers that originate in the lymphatic system from abnormal lymphocytes and can vary widely in aggressiveness and prognosis.
-
A.
Hodgkin
Hodgkin is a surname most famously associated with Dorothy Hodgkin, the Nobel Prize–winning British chemist who advanced the field of X-ray crystallography.
-
B.
Virchow's node
Virchow's node is an enlarged left supraclavicular lymph node that classically indicates metastatic spread from abdominal or thoracic malignancies, especially gastric cancer.
-
C.
SCLC
SCLC is a prominent American civil rights organization founded in 1957 that played a central role in the nonviolent struggle against racial segregation, led in part by Martin Luther King Jr.
-
D.
Rituxan
Rituxan is a monoclonal antibody drug (rituximab) widely used to treat certain blood cancers and autoimmune diseases by targeting the CD20 protein on B cells.
-
E.
TNM
TNM is the IATA airport code for Teniente Rodolfo Marsh Martin Aerodrome, a Chilean airfield located on King George Island in Antarctica.
- F. None of above. chosen
Statements (84)
| Predicate | Object |
|---|---|
| instanceOf |
blood cancer
ⓘ
group of hematologic malignancies ⓘ lymphoid neoplasm ⓘ lymphoma ⓘ |
| hasCellTypeOfOrigin |
B cell
ⓘ
NK cell ⓘ T cell ⓘ lymphocyte ⓘ |
| hasClassification |
aggressive lymphoma
ⓘ
highly aggressive lymphoma ⓘ indolent lymphoma ⓘ |
| hasCommonDrug |
cyclophosphamide
ⓘ
doxorubicin ⓘ prednisone ⓘ rituximab ⓘ
linked to:
Rituxan
vincristine ⓘ |
| hasCommonTreatment |
CAR T-cell therapy
ⓘ
chemotherapy ⓘ immunotherapy ⓘ radiation therapy ⓘ stem cell transplantation ⓘ targeted therapy ⓘ |
| hasEpidemiology |
incidence increases with age
ⓘ
more common in adults than in children ⓘ one of the most common cancers worldwide ⓘ slightly more common in males ⓘ |
| hasInfectiousAssociation |
Epstein–Barr virus infection
ⓘ
linked to:
non-Hodgkin lymphoma
HHV-8 infection ⓘ HTLV-1 infection ⓘ Helicobacter pylori infection ⓘ hepatitis C virus infection ⓘ |
| hasOrigin | lymphatic system ⓘ |
| hasPossibleSymptom |
abdominal pain or fullness
ⓘ
chest pain or cough ⓘ fatigue ⓘ fever ⓘ night sweats ⓘ pruritus ⓘ unintentional weight loss ⓘ |
| hasPrognosticFactor |
age
ⓘ
disease stage ⓘ performance status ⓘ serum LDH level ⓘ |
| hasPrognosticIndex | International Prognostic Index ⓘ |
| hasProperty |
heterogeneous group of diseases
ⓘ
variable aggressiveness ⓘ variable prognosis ⓘ |
| hasRiskFactor |
HIV infection
ⓘ
advanced age ⓘ autoimmune disease ⓘ exposure to benzene ⓘ exposure to certain pesticides ⓘ family history of lymphoma ⓘ immunodeficiency ⓘ organ transplantation ⓘ prior chemotherapy ⓘ prior radiation therapy ⓘ |
| hasSubtype |
Burkitt lymphoma
ⓘ
linked to:
non-Hodgkin lymphoma
NK/T-cell lymphoma, nasal type ⓘ
linked to:
non-Hodgkin lymphoma
Waldenström macroglobulinemia ⓘ
linked to:
non-Hodgkin lymphoma
anaplastic large cell lymphoma ⓘ cutaneous T-cell lymphoma ⓘ diffuse large B-cell lymphoma ⓘ follicular lymphoma ⓘ
linked to:
non-Hodgkin lymphoma
lymphoblastic lymphoma ⓘ mantle cell lymphoma ⓘ marginal zone lymphoma ⓘ peripheral T-cell lymphoma ⓘ
linked to:
non-Hodgkin lymphoma
primary CNS lymphoma ⓘ primary mediastinal large B-cell lymphoma ⓘ small lymphocytic lymphoma ⓘ |
| hasTypicalSymptom | painless lymphadenopathy ⓘ |
| isCharacterizedBy |
abnormal proliferation of lymphocytes
ⓘ
clonal lymphoid cells ⓘ |
| isDiagnosedBy |
cytogenetic analysis
ⓘ
flow cytometry ⓘ histopathologic examination ⓘ immunophenotyping ⓘ lymph node biopsy ⓘ molecular testing ⓘ |
| isDifferentFrom | Hodgkin lymphoma ⓘ |
| isStagedBy |
Ann Arbor staging system
ⓘ
Lugano classification ⓘ |
| partOf | hematologic malignancies ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: non-Hodgkin lymphoma Description of subject: Non-Hodgkin lymphoma is a diverse group of blood cancers that originate in the lymphatic system from abnormal lymphocytes and can vary widely in aggressiveness and prognosis.
Referenced by (41)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
subject linked to:
MabThera SC for subcutaneous formulation
subject linked to:
mitoxantrone
subject linked to:
MS4A1 gene
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma
linked to: non-Hodgkin lymphoma