International Prognostic Index
E436083
The International Prognostic Index is a clinical tool that stratifies patients with aggressive non-Hodgkin lymphoma into risk groups based on factors such as age, disease stage, performance status, extranodal involvement, and serum LDH levels to predict outcomes and guide treatment decisions.
All labels observed (4)
| Label | Occurrences |
|---|---|
| International Prognostic Index canonical | 1 |
| National Comprehensive Cancer Network IPI | 1 |
| age-adjusted International Prognostic Index | 1 |
| revised International Prognostic Index | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T4392587 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: International Prognostic Index Context triple: [non-Hodgkin lymphoma, hasPrognosticIndex, International Prognostic Index]
-
A.
ICD-O
ICD-O (International Classification of Diseases for Oncology) is a specialized coding system used worldwide for classifying tumors by site, morphology, behavior, and grade in cancer registration and research.
-
B.
TNM
TNM is the IATA airport code for Teniente Rodolfo Marsh Martin Aerodrome, a Chilean airfield located on King George Island in Antarctica.
-
C.
IBRA Version 7
IBRA Version 7 is a standardized Australian biogeographic regionalization framework used to classify and map the continent’s distinct ecological regions for conservation and land management planning.
-
D.
R-CHOP
R-CHOP is a standard chemotherapy regimen combining rituximab with multiple cytotoxic drugs, commonly used to treat non-Hodgkin lymphoma.
-
E.
International Classification of Diseases
The International Classification of Diseases is a globally used diagnostic system that standardizes codes for diseases, health conditions, and related medical problems to support clinical care, research, and health statistics.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: International Prognostic Index Target entity description: The International Prognostic Index is a clinical tool that stratifies patients with aggressive non-Hodgkin lymphoma into risk groups based on factors such as age, disease stage, performance status, extranodal involvement, and serum LDH levels to predict outcomes and guide treatment decisions.
-
A.
ICD-O
ICD-O (International Classification of Diseases for Oncology) is a specialized coding system used worldwide for classifying tumors by site, morphology, behavior, and grade in cancer registration and research.
-
B.
TNM
TNM is the IATA airport code for Teniente Rodolfo Marsh Martin Aerodrome, a Chilean airfield located on King George Island in Antarctica.
-
C.
IBRA Version 7
IBRA Version 7 is a standardized Australian biogeographic regionalization framework used to classify and map the continent’s distinct ecological regions for conservation and land management planning.
-
D.
R-CHOP
R-CHOP is a standard chemotherapy regimen combining rituximab with multiple cytotoxic drugs, commonly used to treat non-Hodgkin lymphoma.
-
E.
International Classification of Diseases
The International Classification of Diseases is a globally used diagnostic system that standardizes codes for diseases, health conditions, and related medical problems to support clinical care, research, and health statistics.
- F. None of above. chosen
Statements (50)
| Predicate | Object |
|---|---|
| instanceOf |
clinical prognostic tool
ⓘ
medical scoring system ⓘ oncology prognostic index ⓘ risk stratification model ⓘ |
| ageCutoffYears | 60 ⓘ |
| appliesTo |
aggressive non-Hodgkin lymphoma
ⓘ
diffuse large B-cell lymphoma ⓘ |
| appliesToPopulation | adult patients ⓘ |
| basedOnFactor |
Ann Arbor stage
ⓘ
age ⓘ number of extranodal disease sites ⓘ performance status ⓘ serum lactate dehydrogenase level ⓘ |
| commonlyAbbreviatedAs | IPI ⓘ |
| developedFor |
aggressive lymphomas
ⓘ
high-grade lymphomas ⓘ intermediate-grade lymphomas ⓘ |
| extranodalCriterion | more than one extranodal site ⓘ |
| field |
hematologic malignancies
ⓘ
hematology ⓘ oncology ⓘ |
| hasVariant |
National Comprehensive Cancer Network IPI
ⓘ
linked to:
International Prognostic Index
age-adjusted International Prognostic Index ⓘ
linked to:
International Prognostic Index
revised International Prognostic Index ⓘ
linked to:
International Prognostic Index
|
| influences |
choice of treatment intensity
ⓘ
consideration of autologous stem cell transplantation in high-risk patients ⓘ |
| introducedInDecade | 1990s ⓘ |
| LDHCriterion | elevated serum LDH above normal ⓘ |
| limitation | less accurate in the rituximab era compared with original development era ⓘ |
| measurementType | composite clinical score ⓘ |
| performanceStatusCriterion | ECOG performance status 2 or higher ⓘ |
| purpose |
outcome prediction
ⓘ
prognosis prediction ⓘ risk stratification ⓘ treatment decision support ⓘ |
| riskFactorDefinition |
Ann Arbor stage III or IV disease
ⓘ
age greater than 60 years ⓘ elevated serum LDH ⓘ more than one extranodal site of disease ⓘ poor performance status ⓘ |
| riskGroup |
high risk
ⓘ
high-intermediate risk ⓘ low risk ⓘ low-intermediate risk ⓘ |
| riskGroupBasis | number of adverse prognostic factors ⓘ |
| stageCriterion | Ann Arbor stage III or IV ⓘ |
| usedFor |
clinical trial stratification
ⓘ
comparisons of treatment outcomes ⓘ patient counseling ⓘ |
| usesPerformanceScale | ECOG performance status ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: International Prognostic Index Description of subject: The International Prognostic Index is a clinical tool that stratifies patients with aggressive non-Hodgkin lymphoma into risk groups based on factors such as age, disease stage, performance status, extranodal involvement, and serum LDH levels to predict outcomes and guide treatment decisions.
Referenced by (4)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: International Prognostic Index
linked to: International Prognostic Index
linked to: International Prognostic Index