Wegener's granulomatosis

E105929

autoimmune disease granulomatous disease rare disease systemic vasculitis

Wegener's granulomatosis, now more commonly called granulomatosis with polyangiitis, is a rare autoimmune disease characterized by inflammation of blood vessels that can damage organs such as the lungs, kidneys, and upper respiratory tract.

Try in SPARQL Jump to: Surface forms Disambiguation Statements Elicitation Referenced by

All labels observed (8)

Label	Occurrences
granulomatosis with polyangiitis	6
Wegener's granulomatosis canonical	4
ANCA-associated vasculitis	1
Granulomatosis with polyangiitis	1
Wegener	1
Wegener granulomatosis	1
Wegener vasculitis	1
granulomatosis with polyangiitis (Wegener's)	1

How this entity was disambiguated

This entity first appeared as the object of triple T891749 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.

NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07

Target entity: Wegener's granulomatosis
Context triple: [Heinrich Hertz, causeOfDeath, Wegener's granulomatosis]

A. SLE
SLE is a mid-level trim package for GMC vehicles that typically adds upgraded comfort, convenience, and appearance features over the base model.
B. Kerkinitis
Kerkinitis is an ancient Greek colony on the Crimean coast, later known as Eupatoria, that served as an important Black Sea trading settlement.
C. Virchow's triad
Virchow's triad is a medical concept describing the three primary factors that contribute to the formation of blood clots: endothelial injury, abnormal blood flow, and hypercoagulability.
D. Hodgkin
Hodgkin is a surname most famously associated with Dorothy Hodgkin, the Nobel Prize–winning British chemist who advanced the field of X-ray crystallography.
E. Northgrippian
The Northgrippian is the middle age of the Holocene epoch, defined by a significant global cooling event that occurred around 4,200 years ago.
F. None of above. chosen
G. Unsure - the case is ambiguous/there is not enough information to decide.

NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07

Target entity: Wegener's granulomatosis
Target entity description: Wegener's granulomatosis, now more commonly called granulomatosis with polyangiitis, is a rare autoimmune disease characterized by inflammation of blood vessels that can damage organs such as the lungs, kidneys, and upper respiratory tract.

A. SLE
SLE is a mid-level trim package for GMC vehicles that typically adds upgraded comfort, convenience, and appearance features over the base model.
B. Kerkinitis
Kerkinitis is an ancient Greek colony on the Crimean coast, later known as Eupatoria, that served as an important Black Sea trading settlement.
C. Virchow's triad
Virchow's triad is a medical concept describing the three primary factors that contribute to the formation of blood clots: endothelial injury, abnormal blood flow, and hypercoagulability.
D. Hodgkin
Hodgkin is a surname most famously associated with Dorothy Hodgkin, the Nobel Prize–winning British chemist who advanced the field of X-ray crystallography.
E. Northgrippian
The Northgrippian is the middle age of the Holocene epoch, defined by a significant global cooling event that occurred around 4,200 years ago.
F. None of above. chosen

Statements (65)

Predicate	Object
instanceOf	autoimmune disease ⓘ granulomatous disease ⓘ rare disease ⓘ systemic vasculitis ⓘ
affectsSystem	lower respiratory tract ⓘ renal system ⓘ respiratory system ⓘ upper respiratory tract ⓘ vascular system ⓘ
associatedWithAntibody	anti-proteinase 3 antibody ⓘ
canCause	chronic sinusitis ⓘ glomerulonephritis ⓘ hematuria ⓘ otitis media ⓘ proteinuria ⓘ pulmonary hemorrhage ⓘ pulmonary nodules ⓘ saddle-nose deformity ⓘ
hasAbbreviation	GPA ⓘ
hasBiomarker	PR3-ANCA ⓘ c-ANCA ⓘ
hasClassification	ANCA-associated vasculitis ⓘ linked to: Wegener's granulomatosis small-vessel vasculitis ⓘ
hasCourse	chronic relapsing course ⓘ
hasDiagnosticTest	ANCA test ⓘ chest CT scan ⓘ tissue biopsy ⓘ urinalysis ⓘ
hasEponym	Friedrich Wegener ⓘ
hasEtiology	autoimmune mechanism ⓘ
hasICD10Code	M31.3 ⓘ
hasPathologyFeature	medium-vessel vasculitis ⓘ necrotizing granulomatous inflammation ⓘ necrotizing vasculitis ⓘ small-vessel vasculitis ⓘ
hasPreferredName	granulomatosis with polyangiitis ⓘ linked to: Wegener's granulomatosis
hasPrognosis	potentially life-threatening ⓘ
hasSymptom	arthralgia ⓘ cough ⓘ dyspnea ⓘ epistaxis ⓘ fatigue ⓘ fever ⓘ hemoptysis ⓘ nasal congestion ⓘ weight loss ⓘ
hasSynonym	Wegener granulomatosis ⓘ linked to: Wegener's granulomatosis Wegener vasculitis ⓘ linked to: Wegener's granulomatosis granulomatosis with polyangiitis (Wegener's) ⓘ linked to: Wegener's granulomatosis
hasTreatmentPhase	induction therapy ⓘ maintenance therapy ⓘ
moreCommonIn	adults ⓘ middle-aged individuals ⓘ
recognizedBy	American College of Rheumatology ⓘ Chapel Hill Consensus Conference on Vasculitis Nomenclature ⓘ
treatedWith	azathioprine ⓘ cyclophosphamide ⓘ glucocorticoids ⓘ methotrexate ⓘ mycophenolate mofetil ⓘ rituximab ⓘ linked to: Rituxan
typicalLesionSite	kidneys ⓘ lungs ⓘ nasal cavity ⓘ paranasal sinuses ⓘ

How these facts were elicited