doseAdjustmentRequiredIn

P61679
predicate

Indicates that a change in the amount or frequency of a treatment or medication is necessary within a specified context, such as a condition, setting, or patient group.

All labels observed (6)

Label Occurrences
requiresDoseAdjustmentIn 6
doseAdjustmentRequiredIn canonical 2
mayRequireDoseModificationIn 2

Description generation (PDg)

The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.

Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning.  
# Instructions
Focus on describing the relationship, not the entities themselves. 
# Response Format
Begin the description with \' Indicates...\'
Input
Predicate: doseAdjustmentRequiredIn
Generated description
Indicates that a change in the amount or frequency of a treatment or medication is necessary within a specified context, such as a condition, setting, or patient group.

Sample triples (13)

Subject Object
Memantine
linked to: memantine
severe renal impairment ⓘ
Cymbalta hepatic impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ
amantadine renal impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ
Xeloda renal impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ
warfarin true via predicate surface "requiresRegularDoseAdjustment" ⓘ
Januvia renal impairment ⓘ
Lyrica renal impairment via predicate surface "requiresAdjustmentIn" ⓘ
Ebixa renal impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ
ABVD regimen renal impairment via predicate surface "mayRequireDoseModificationIn" ⓘ
ABVD regimen hepatic impairment via predicate surface "mayRequireDoseModificationIn" ⓘ
FOLFIRI regimen dose reduction may be required in patients with UGT1A1*28 polymorphism for irinotecan via predicate surface "doseAdjustment" ⓘ
DOAC renal impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ
DOAC hepatic impairment via predicate surface "requiresDoseAdjustmentIn" ⓘ