Ebixa

E494106

Ebixa is a brand-name medication containing memantine, used primarily to treat moderate to severe Alzheimer's disease.

All labels observed (1)

Label Occurrences
Ebixa canonical 1

How this entity was disambiguated

Statements (47)

Predicate Object
instanceOf brand-name medication ⓘ
memantine-containing medicinal product ⓘ
actsOn N-methyl-D-aspartate (NMDA) receptors ⓘ
administrationFrequency once daily (maintenance dose) ⓘ
ATCCode N06DX01 ⓘ
belongsTo centrally acting anti-dementia drugs ⓘ
commonAdverseEffect confusion ⓘ
constipation ⓘ
dizziness ⓘ
headache ⓘ
hypertension ⓘ
somnolence ⓘ
contraindication hypersensitivity to memantine ⓘ
developedBy H. Lundbeck A/S ⓘ
linked to: Lundbeck
dosageForm film-coated tablet ⓘ
oral solution ⓘ
drugInteractionCaution amantadine ⓘ
dextromethorphan ⓘ
ketamine ⓘ
other NMDA antagonists ⓘ
elimination primarily renal excretion ⓘ
halfLife about 60–80 hours ⓘ
hasActiveIngredient memantine ⓘ
improves cognitive function in Alzheimer's disease ⓘ
global functioning in Alzheimer's disease ⓘ
indication moderate Alzheimer's disease ⓘ
severe Alzheimer's disease ⓘ
isBrandOf memantine hydrochloride ⓘ
marketingAuthorizationHolder Lundbeck ⓘ
marketingAuthorizationRegion European Union ⓘ
maximumDailyDose 20 mg memantine (typical in adults) ⓘ
maySlow clinical deterioration in Alzheimer's disease ⓘ
metabolism minimally metabolized in the liver ⓘ
notIndicatedFor mild Alzheimer's disease ⓘ
pharmacologicalClass NMDA receptor antagonist ⓘ
regulates glutamatergic neurotransmission ⓘ
requires prescription ⓘ
requiresCautionIn severe renal impairment ⓘ
requiresDoseAdjustmentIn renal impairment ⓘ
routeOfAdministration oral ⓘ
targetPopulation adult patients ⓘ
elderly patients ⓘ
therapeuticArea geriatrics ⓘ
neurology ⓘ
titration requires gradual dose escalation ⓘ
treats Alzheimer's disease ⓘ
usedIn symptomatic treatment of Alzheimer's disease ⓘ

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

Memantine → isMarketedUnderBrandName → Ebixa ⓘ
subject linked to: memantine