Lyrica
E474930
Lyrica is a prescription medication (pregabalin) commonly used to treat nerve pain, fibromyalgia, and certain types of seizures.
All labels observed (2)
| Label | Occurrences |
|---|---|
| pregabalin | 2 |
| Lyrica canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T4850378 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Lyrica Context triple: [Pfizer, developed, Lyrica]
-
A.
Cymbalta
Cymbalta is a prescription antidepressant medication (duloxetine) commonly used to treat major depressive disorder, generalized anxiety disorder, and certain types of chronic pain.
-
B.
Motrin
Motrin is a widely used over-the-counter ibuprofen pain reliever and fever reducer medication.
-
C.
Daypro
Daypro is a prescription nonsteroidal anti-inflammatory drug (NSAID) containing oxaprozin, used to relieve pain and inflammation in conditions such as osteoarthritis and rheumatoid arthritis.
-
D.
Anpezan
Anpezan is a regional dialect of the Ladin language spoken in parts of the Dolomite area of northern Italy.
-
E.
riluzole
Riluzole is a neuroprotective medication that modestly prolongs survival and slows disease progression in people with amyotrophic lateral sclerosis (ALS).
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Lyrica Target entity description: Lyrica is a prescription medication (pregabalin) commonly used to treat nerve pain, fibromyalgia, and certain types of seizures.
-
A.
Cymbalta
Cymbalta is a prescription antidepressant medication (duloxetine) commonly used to treat major depressive disorder, generalized anxiety disorder, and certain types of chronic pain.
-
B.
Motrin
Motrin is a widely used over-the-counter ibuprofen pain reliever and fever reducer medication.
-
C.
Daypro
Daypro is a prescription nonsteroidal anti-inflammatory drug (NSAID) containing oxaprozin, used to relieve pain and inflammation in conditions such as osteoarthritis and rheumatoid arthritis.
-
D.
Anpezan
Anpezan is a regional dialect of the Ladin language spoken in parts of the Dolomite area of northern Italy.
-
E.
riluzole
Riluzole is a neuroprotective medication that modestly prolongs survival and slows disease progression in people with amyotrophic lateral sclerosis (ALS).
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
brand name drug
ⓘ
medication ⓘ |
| affectsSystem | central nervous system ⓘ |
| approvedBy |
U.S. Food and Drug Administration
ⓘ
linked to:
Food and Drug Administration
|
| approvedIn |
European Union
ⓘ
United States ⓘ
linked to:
United States of America
|
| availableAs |
extended-release tablet
ⓘ
oral capsule ⓘ oral solution ⓘ |
| controlledSubstanceSchedule | Schedule V in the United States ⓘ |
| developedBy | Pfizer ⓘ |
| FDAApprovalYear | 2005 ⓘ |
| firstApprovedRegion | European Union ⓘ |
| firstApprovedYear | 2004 ⓘ |
| hasActiveIngredient |
pregabalin
ⓘ
linked to:
Lyrica
|
| hasATCCode | N03AX16 ⓘ |
| hasBlackBoxWarning | risk of suicidal thoughts and behavior with antiepileptic drugs ⓘ |
| hasCommonSideEffect |
blurred vision
ⓘ
difficulty concentrating ⓘ dizziness ⓘ dry mouth ⓘ peripheral edema ⓘ somnolence ⓘ weight gain ⓘ |
| hasDrugClass |
anticonvulsant
ⓘ
antiepileptic drug ⓘ gabapentinoid ⓘ |
| hasEliminationHalfLife | about 6 hours in adults with normal renal function ⓘ |
| hasGenericName | pregabalin ⓘ |
| hasRisk |
dependence potential
ⓘ
misuse potential ⓘ withdrawal symptoms on abrupt discontinuation ⓘ |
| indicatedPopulation | adults ⓘ |
| isFormulationOf | pregabalin ⓘ |
| isNotRecommendedWith | concurrent alcohol use due to additive CNS depression ⓘ |
| legalStatus | prescription only ⓘ |
| mechanismOfAction | binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system ⓘ |
| pregnancyCategory | Category C (US, historical) ⓘ |
| primaryRouteOfElimination | renal ⓘ |
| requiresAdjustmentIn | renal impairment ⓘ |
| routeOfAdministration | oral ⓘ |
| treatsCondition |
diabetic peripheral neuropathy
ⓘ
fibromyalgia ⓘ focal seizures ⓘ neuropathic pain ⓘ neuropathic pain associated with spinal cord injury ⓘ partial-onset seizures ⓘ postherpetic neuralgia ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Lyrica Description of subject: Lyrica is a prescription medication (pregabalin) commonly used to treat nerve pain, fibromyalgia, and certain types of seizures.
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: Lyrica
linked to: Lyrica