Prozac
E135132
Prozac is a widely prescribed antidepressant medication (fluoxetine) used to treat major depressive disorder, anxiety disorders, and certain other mental health conditions.
All labels observed (2)
| Label | Occurrences |
|---|---|
| Prozac canonical | 4 |
| fluoxetine hydrochloride | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T1168573 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Prozac Context triple: [Eli Lilly and Company, notableProduct, Prozac]
-
A.
Cymbalta
Cymbalta is a prescription antidepressant medication (duloxetine) commonly used to treat major depressive disorder, generalized anxiety disorder, and certain types of chronic pain.
-
B.
Anpezan
Anpezan is a regional dialect of the Ladin language spoken in parts of the Dolomite area of northern Italy.
-
C.
Tylenol
Tylenol is a widely used over-the-counter pain reliever and fever reducer whose active ingredient is acetaminophen (paracetamol).
-
D.
Denesuline
Denesuline are a First Nations people of the larger Dene cultural and linguistic group, traditionally inhabiting subarctic regions of northern Canada.
-
E.
Donepezil
Donepezil is a cholinesterase inhibitor medication primarily used to treat cognitive symptoms of Alzheimer's disease.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Prozac Target entity description: Prozac is a widely prescribed antidepressant medication (fluoxetine) used to treat major depressive disorder, anxiety disorders, and certain other mental health conditions.
-
A.
Cymbalta
Cymbalta is a prescription antidepressant medication (duloxetine) commonly used to treat major depressive disorder, generalized anxiety disorder, and certain types of chronic pain.
-
B.
Anpezan
Anpezan is a regional dialect of the Ladin language spoken in parts of the Dolomite area of northern Italy.
-
C.
Tylenol
Tylenol is a widely used over-the-counter pain reliever and fever reducer whose active ingredient is acetaminophen (paracetamol).
-
D.
Denesuline
Denesuline are a First Nations people of the larger Dene cultural and linguistic group, traditionally inhabiting subarctic regions of northern Canada.
-
E.
Donepezil
Donepezil is a cholinesterase inhibitor medication primarily used to treat cognitive symptoms of Alzheimer's disease.
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
antidepressant medication
ⓘ
brand name drug ⓘ selective serotonin reuptake inhibitor ⓘ |
| affects | serotonin reuptake ⓘ |
| hasActiveIngredient |
fluoxetine hydrochloride
ⓘ
linked to:
Prozac
|
| hasATCCode | N06AB03 ⓘ |
| hasBlackBoxWarningFor | suicidal thoughts and behaviors in children, adolescents, and young adults ⓘ |
| hasBrandName | Prozac ⓘ |
| hasChemicalClass | phenylpropylamine derivative ⓘ |
| hasCommonSideEffect |
anxiety
ⓘ
dry mouth ⓘ headache ⓘ insomnia ⓘ nausea ⓘ sexual dysfunction ⓘ |
| hasDefinedDailyDose | 20 mg (oral) ⓘ |
| hasDosageForm |
capsule
ⓘ
oral solution ⓘ tablet ⓘ |
| hasEliminationRoute |
hepatic
ⓘ
renal ⓘ |
| hasGenericName | fluoxetine ⓘ |
| hasHalfLife |
about 2 to 4 days for fluoxetine
ⓘ
about 7 to 15 days for norfluoxetine ⓘ |
| hasLegalStatus | prescription only ⓘ |
| hasMechanismOfAction | inhibition of serotonin reuptake in the presynaptic neuron ⓘ |
| hasRouteOfAdministration | oral ⓘ |
| hasSeriousSideEffect |
QT interval prolongation
ⓘ
serotonin syndrome ⓘ suicidal thoughts and behaviors ⓘ |
| isApprovedBy |
U.S. Food and Drug Administration
ⓘ
linked to:
Food and Drug Administration
|
| isContraindicatedWith |
monoamine oxidase inhibitors
ⓘ
pimozide ⓘ thioridazine ⓘ |
| isListedOn | World Health Organization Model List of Essential Medicines ⓘ |
| isManufacturedBy | Eli Lilly and Company ⓘ |
| isMetabolizedBy |
CYP2C19
ⓘ
CYP2C9 ⓘ CYP2D6 ⓘ |
| isPregnancyCategory | C (U.S., historical classification) ⓘ |
| isUsedInCombinationWith | olanzapine for treatment-resistant depression ⓘ |
| treats |
anxiety disorders
ⓘ
bulimia nervosa ⓘ major depressive disorder ⓘ obsessive–compulsive disorder ⓘ panic disorder ⓘ premenstrual dysphoric disorder ⓘ |
| wasFirstApprovedIn | 1987 ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Prozac Description of subject: Prozac is a widely prescribed antidepressant medication (fluoxetine) used to treat major depressive disorder, anxiety disorders, and certain other mental health conditions.
Referenced by (5)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: Prozac
subject linked to:
Eli Lilly and Company (former executive roles prior to governorship)