Vumerity
E24937
Vumerity is an oral prescription medication used to treat relapsing forms of multiple sclerosis in adults.
All labels observed (2)
| Label | Occurrences |
|---|---|
| diroximel fumarate | 2 |
| Vumerity canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T195377 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Vumerity Context triple: [Biogen, hasProduct, Vumerity]
-
A.
Plegridy
Plegridy is a pegylated interferon beta-1a medication used to treat relapsing forms of multiple sclerosis.
-
B.
Kimvita
Kimvita is a major coastal dialect of Swahili spoken primarily in and around Mombasa, Kenya.
-
C.
Pregny-Chambésy
Pregny-Chambésy is a small, affluent municipality on the shores of Lake Geneva in the canton of Geneva, Switzerland, known for hosting several international organizations and diplomatic missions.
-
D.
Philortyx
Philortyx is a genus of New World quails known for their ground-dwelling habits and occurrence in scrub and grassland habitats of the Americas.
-
E.
Abital
Abital is one of the lesser-known wives of the biblical King David, mentioned in the Hebrew Bible as the mother of his son Shephatiah.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Vumerity Target entity description: Vumerity is an oral prescription medication used to treat relapsing forms of multiple sclerosis in adults.
-
A.
Plegridy
Plegridy is a pegylated interferon beta-1a medication used to treat relapsing forms of multiple sclerosis.
-
B.
Kimvita
Kimvita is a major coastal dialect of Swahili spoken primarily in and around Mombasa, Kenya.
-
C.
Pregny-Chambésy
Pregny-Chambésy is a small, affluent municipality on the shores of Lake Geneva in the canton of Geneva, Switzerland, known for hosting several international organizations and diplomatic missions.
-
D.
Philortyx
Philortyx is a genus of New World quails known for their ground-dwelling habits and occurrence in scrub and grassland habitats of the Americas.
-
E.
Abital
Abital is one of the lesser-known wives of the biblical King David, mentioned in the Hebrew Bible as the mother of his son Shephatiah.
- F. None of above. chosen
Statements (46)
| Predicate | Object |
|---|---|
| instanceOf |
multiple sclerosis therapy
ⓘ
pharmaceutical drug ⓘ prescription medication ⓘ |
| belongsToRegimenType | disease-modifying therapy for multiple sclerosis ⓘ |
| brandOf |
diroximel fumarate
ⓘ
linked to:
Vumerity
|
| chemicallyRelatedTo | dimethyl fumarate ⓘ |
| commonAdverseEffect |
abdominal pain
ⓘ
diarrhea ⓘ flushing ⓘ nausea ⓘ |
| contraindicatedIn |
known hypersensitivity to dimethyl fumarate
ⓘ
known hypersensitivity to diroximel fumarate ⓘ |
| developedBy |
Alkermes
ⓘ
Biogen ⓘ |
| FDAApprovalYear | 2019 ⓘ |
| foodEffect |
may be taken with or without food
ⓘ
taking with food may reduce flushing ⓘ |
| hasAdministrationFrequency | twice daily ⓘ |
| hasDosageForm | delayed-release capsule ⓘ |
| hasGenericName |
diroximel fumarate
ⓘ
linked to:
Vumerity
|
| hasInitialDoseRegimen | lower dose for first 7 days ⓘ |
| hasMaintenanceDoseRegimen | higher dose after first week ⓘ |
| hasMechanismOfAction |
fumarate derivative
ⓘ
thought to activate the Nrf2 pathway ⓘ |
| hasPharmacologicClass |
fumaric acid ester
ⓘ
immunomodulator ⓘ |
| hasPregnancyCategory | risk not ruled out ⓘ |
| hasRegulatoryApproval |
U.S. Food and Drug Administration
ⓘ
linked to:
Food and Drug Administration
|
| hasRouteOfAdministration | oral ⓘ |
| hasRouteWarning | do not crush, chew, or sprinkle capsule contents ⓘ |
| hasTherapeuticGoal |
reduce MRI lesion activity in multiple sclerosis
ⓘ
reduce relapse rate in multiple sclerosis ⓘ slow disability progression in multiple sclerosis ⓘ |
| indicatedFor |
active secondary progressive multiple sclerosis
ⓘ
clinically isolated syndrome ⓘ relapsing forms of multiple sclerosis ⓘ relapsing-remitting multiple sclerosis ⓘ |
| indicatedPopulation | adults ⓘ |
| isTakenWith | water ⓘ |
| marketedBy | Biogen ⓘ |
| metabolizedTo | monomethyl fumarate ⓘ |
| requiresMonitoring |
liver function tests
ⓘ
lymphocyte counts ⓘ |
| seriousAdverseEffect |
liver injury
ⓘ
lymphopenia ⓘ progressive multifocal leukoencephalopathy ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Vumerity Description of subject: Vumerity is an oral prescription medication used to treat relapsing forms of multiple sclerosis in adults.
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: Vumerity