relapsing-remitting multiple sclerosis
E121346
autoimmune disease subtype
clinical course subtype of multiple sclerosis
neurological disease subtype
Relapsing-remitting multiple sclerosis is the most common form of multiple sclerosis, characterized by clearly defined attacks of neurological symptoms followed by periods of partial or complete recovery.
All labels observed (1)
| Label | Occurrences |
|---|---|
| relapsing-remitting multiple sclerosis canonical | 3 |
How this entity was disambiguated
This entity first appeared as the object of triple T1056820 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: relapsing-remitting multiple sclerosis Context triple: [Josiah Bartlet, medicalCondition, relapsing-remitting multiple sclerosis]
-
A.
MS
MS is the official two-letter United States Postal Service abbreviation for the state of Mississippi.
-
B.
MS
MS is the two-letter ISO 3166 country code assigned to the British Overseas Territory of Montserrat in the Caribbean.
-
C.
Tecfidera
Tecfidera is an oral disease-modifying medication used to treat relapsing forms of multiple sclerosis by reducing inflammation and relapse frequency.
-
D.
Tysabri
Tysabri is a monoclonal antibody medication primarily used to treat relapsing forms of multiple sclerosis and Crohn’s disease.
-
E.
SLE
SLE is a mid-level trim package for GMC vehicles that typically adds upgraded comfort, convenience, and appearance features over the base model.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: relapsing-remitting multiple sclerosis Target entity description: Relapsing-remitting multiple sclerosis is the most common form of multiple sclerosis, characterized by clearly defined attacks of neurological symptoms followed by periods of partial or complete recovery.
-
A.
MS
MS is the official two-letter United States Postal Service abbreviation for the state of Mississippi.
-
B.
MS
MS is the two-letter ISO 3166 country code assigned to the British Overseas Territory of Montserrat in the Caribbean.
-
C.
Tecfidera
Tecfidera is an oral disease-modifying medication used to treat relapsing forms of multiple sclerosis by reducing inflammation and relapse frequency.
-
D.
Tysabri
Tysabri is a monoclonal antibody medication primarily used to treat relapsing forms of multiple sclerosis and Crohn’s disease.
-
E.
SLE
SLE is a mid-level trim package for GMC vehicles that typically adds upgraded comfort, convenience, and appearance features over the base model.
- F. None of above. chosen
Statements (51)
| Predicate | Object |
|---|---|
| instanceOf |
autoimmune disease subtype
ⓘ
clinical course subtype of multiple sclerosis ⓘ neurological disease subtype ⓘ |
| affectsAnatomicalLocation |
brain
ⓘ
central nervous system ⓘ spinal cord ⓘ |
| canProgressTo | secondary progressive multiple sclerosis ⓘ |
| characterizedBy |
clearly defined relapses of neurological dysfunction
ⓘ
episodes of new or worsening neurological symptoms ⓘ periods of partial or complete remission ⓘ |
| commonSymptom |
ataxia
ⓘ
bladder dysfunction ⓘ cognitive impairment ⓘ fatigue ⓘ motor weakness ⓘ optic neuritis ⓘ sensory disturbances ⓘ |
| diagnosedBy |
MRI evidence of demyelinating lesions disseminated in time and space
ⓘ
clinical history of relapses and remissions ⓘ exclusion of alternative diagnoses ⓘ |
| epidemiology |
accounts for majority of multiple sclerosis cases at diagnosis
ⓘ
more prevalent in regions with higher latitude ⓘ |
| hasAbbreviation | RRMS ⓘ |
| hasCoursePattern |
relapsing
ⓘ
remitting ⓘ |
| hasPrognosis |
better early prognosis than progressive forms of multiple sclerosis
ⓘ
variable long-term disability accumulation ⓘ |
| hasSexPredominance | more common in females than males ⓘ |
| hasUnderlyingMechanism |
immune-mediated demyelination in central nervous system
ⓘ
inflammatory lesions in brain and spinal cord ⓘ |
| isMostCommonFormOf | multiple sclerosis ⓘ |
| mayShowOnMRI |
T2 hyperintense lesions in white matter
ⓘ
gadolinium-enhancing lesions during relapses ⓘ |
| partOf | multiple sclerosis disease spectrum ⓘ |
| relapseDuration | at least 24 hours ⓘ |
| relapseSeparationInterval | at least 30 days between attacks ⓘ |
| relapseTreatment | high-dose corticosteroids ⓘ |
| remissionCharacteristic |
complete recovery of function in some patients
ⓘ
partial recovery of function ⓘ |
| riskFactor |
genetic susceptibility
ⓘ
prior Epstein–Barr virus infection ⓘ smoking ⓘ vitamin D deficiency ⓘ |
| treatedWith |
disease-modifying therapies
ⓘ
fingolimod ⓘ glatiramer acetate ⓘ interferon beta preparations ⓘ natalizumab ⓘ
linked to:
Tysabri
ocrelizumab ⓘ |
| typicalOnsetAgeRange |
20–40 years
ⓘ
early adulthood ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: relapsing-remitting multiple sclerosis Description of subject: Relapsing-remitting multiple sclerosis is the most common form of multiple sclerosis, characterized by clearly defined attacks of neurological symptoms followed by periods of partial or complete recovery.
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.