LGS

E939685

LGS is a severe, childhood-onset epileptic encephalopathy characterized by multiple types of seizures, cognitive impairment, and a distinctive EEG pattern.

All labels observed (1)

Label Occurrences
LGS canonical 3

How this entity was disambiguated

Statements (53)

Predicate Object
instanceOf epileptic encephalopathy ⓘ
neurological disorder ⓘ
rare disease ⓘ
affects both males and females ⓘ
children ⓘ
canBeIdiopathic true ⓘ
hasAbbreviation LGS ⓘ
hasCause central nervous system infections ⓘ
cortical malformations ⓘ
genetic disorders ⓘ
hypoxic–ischemic encephalopathy ⓘ
perinatal brain injury ⓘ
structural brain abnormalities ⓘ
tuberous sclerosis complex ⓘ
hasCourse chronic ⓘ
treatment-resistant ⓘ
hasEEGPattern paroxysmal fast activity in sleep ⓘ
slow spike-and-wave discharges ⓘ
hasICD10Code G40.4 ⓘ
hasIncidence rare ⓘ
hasOnset childhood ⓘ
hasPrognosis high risk of persistent seizures into adulthood ⓘ
often poor ⓘ
hasSeizureType atonic seizures ⓘ
atypical absence seizures ⓘ
focal seizures ⓘ
generalized tonic–clonic seizures ⓘ
myoclonic seizures ⓘ
tonic seizures ⓘ
hasSymptom behavioral problems ⓘ
developmental delay ⓘ
frequent falls due to drop attacks ⓘ
intellectual disability ⓘ
isAssociatedWith autism spectrum disorder ⓘ
behavioral dysregulation ⓘ
sleep disturbances ⓘ
status epilepticus ⓘ
isCharacterizedBy cognitive impairment ⓘ
distinctive EEG pattern ⓘ
multiple seizure types ⓘ
isTreatedWith cannabidiol ⓘ
clobazam ⓘ
corpus callosotomy ⓘ
felbamate ⓘ
ketogenic diet ⓘ
lamotrigine ⓘ
rufinamide ⓘ
topiramate ⓘ
vagus nerve stimulation ⓘ
valproate ⓘ
namedAfter Henri Gastaut ⓘ
William G. Lennox NERFINISHED ⓘ
typicalAgeOfOnset between 3 and 5 years ⓘ

How these facts were elicited

Referenced by (3)

Full triples — surface form annotated when it differs from this entity's canonical label.

Lennox–Gastaut syndrome → hasAbbreviation → LGS ⓘ
subject linked to: LGS