Human mastadenovirus D
E854990
Human mastadenovirus D is a species of human adenoviruses that includes multiple serotypes, some of which are used as viral vectors in vaccine development and gene therapy.
All labels observed (2)
| Label | Occurrences |
|---|---|
| Human adenovirus D | 1 |
| Human mastadenovirus D canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T10292276 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Human mastadenovirus D Context triple: [human adenovirus serotype 26, taxonomicGroup, Human mastadenovirus D]
-
A.
John Cunningham virus
John Cunningham virus is a human polyomavirus that typically remains latent but can cause the severe demyelinating brain disease progressive multifocal leukoencephalopathy in immunocompromised individuals.
-
B.
vesicular stomatitis virus
Vesicular stomatitis virus is an enveloped, negative-sense RNA virus of the Rhabdoviridae family that primarily infects livestock and is widely used as a viral vector in vaccine development and virology research.
-
C.
Vircava
Vircava is a river in Latvia that serves as one of the tributaries feeding into the larger Lielupe River system.
-
D.
Reston ebolavirus
Reston ebolavirus is a species of ebolavirus that primarily infects nonhuman primates and pigs and is notable for being the only known ebolavirus that has caused asymptomatic infections in humans.
-
E.
Vireolanius
Vireolanius is a small genus of Neotropical birds known as shrike-vireos, characterized by their robust bills and vibrant plumage.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Human mastadenovirus D Target entity description: Human mastadenovirus D is a species of human adenoviruses that includes multiple serotypes, some of which are used as viral vectors in vaccine development and gene therapy.
-
A.
John Cunningham virus
John Cunningham virus is a human polyomavirus that typically remains latent but can cause the severe demyelinating brain disease progressive multifocal leukoencephalopathy in immunocompromised individuals.
-
B.
vesicular stomatitis virus
Vesicular stomatitis virus is an enveloped, negative-sense RNA virus of the Rhabdoviridae family that primarily infects livestock and is widely used as a viral vector in vaccine development and virology research.
-
C.
Vircava
Vircava is a river in Latvia that serves as one of the tributaries feeding into the larger Lielupe River system.
-
D.
Reston ebolavirus
Reston ebolavirus is a species of ebolavirus that primarily infects nonhuman primates and pigs and is notable for being the only known ebolavirus that has caused asymptomatic infections in humans.
-
E.
Vireolanius
Vireolanius is a small genus of Neotropical birds known as shrike-vireos, characterized by their robust bills and vibrant plumage.
- F. None of above. chosen
Statements (46)
| Predicate | Object |
|---|---|
| instanceOf |
human adenovirus
ⓘ
virus species ⓘ |
| associatedWithDisease |
conjunctivitis
ⓘ
epidemic keratoconjunctivitis ⓘ gastroenteritis ⓘ pharyngoconjunctival fever ⓘ respiratory tract infections ⓘ |
| BaltimoreClassification | Group I dsDNA virus ⓘ |
| biosafetyLevel | typically handled at BSL-2 in laboratories ⓘ |
| capsidComposition | protein capsid ⓘ |
| capsidSymmetry | icosahedral ⓘ |
| clinicalRelevance |
important cause of ocular adenovirus infections
ⓘ
important in adenoviral vector design ⓘ |
| contains | multiple serotypes ⓘ |
| enveloped | non-enveloped ⓘ |
| environmentalStability | stable in the environment ⓘ |
| family | Adenoviridae ⓘ |
| genomeSegmented | non-segmented ⓘ |
| genomeStructure | linear double-stranded DNA ⓘ |
| genomeType | double-stranded DNA virus ⓘ |
| genus | Mastadenovirus ⓘ |
| hasGenome | linear dsDNA of approximately 34–36 kilobase pairs ⓘ |
| host | Homo sapiens ⓘ |
| infects |
human conjunctival epithelial cells
ⓘ
human gastrointestinal epithelium ⓘ human respiratory tract epithelium ⓘ |
| naturalHost | human ⓘ |
| nucleicAcidType | DNA ⓘ |
| parentTaxon |
Adenoviridae
ⓘ
Human adenovirus D ⓘ
linked to:
Human mastadenovirus D
Mastadenovirus ⓘ |
| particleType | non-segmented virion ⓘ |
| pathogenicFor |
immunocompetent humans
ⓘ
immunocompromised humans ⓘ |
| receptorUsage |
CD46 (for some serotypes)
ⓘ
linked to:
CD46
sialic acid-containing glycans (for several serotypes) ⓘ |
| replicationCycle | lytic in permissive human cells ⓘ |
| replicationSite | nucleus of host cell ⓘ |
| resistance | resistant to many common disinfectants ⓘ |
| taxonRank | species ⓘ |
| transmissionRoute |
direct contact with contaminated surfaces
ⓘ
fecal-oral route ⓘ respiratory droplets ⓘ |
| usedAs | viral vector ⓘ |
| usedIn |
gene therapy research
ⓘ
vaccine development ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Human mastadenovirus D Description of subject: Human mastadenovirus D is a species of human adenoviruses that includes multiple serotypes, some of which are used as viral vectors in vaccine development and gene therapy.
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject linked to:
human adenovirus serotype 26 (Ad26)
linked to: Human mastadenovirus D