oseltamivir
E85057
Oseltamivir is an oral antiviral medication (commonly known by the brand name Tamiflu) used to treat and prevent influenza, including pandemic strains such as 2009 H1N1.
All labels observed (2)
| Label | Occurrences |
|---|---|
| Tamiflu | 3 |
| oseltamivir canonical | 2 |
How this entity was disambiguated
This entity first appeared as the object of triple T701554 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: oseltamivir Context triple: [2009 H1N1 influenza pandemic, antiviralTreatment, oseltamivir]
-
A.
Leqembi
Leqembi is an Alzheimer’s disease drug (lecanemab) that targets amyloid-beta plaques to slow cognitive decline in early-stage patients.
-
B.
Vumerity
Vumerity is an oral prescription medication used to treat relapsing forms of multiple sclerosis in adults.
-
C.
Plegridy
Plegridy is a pegylated interferon beta-1a medication used to treat relapsing forms of multiple sclerosis.
-
D.
Activase
Activase is a brand-name form of the clot-dissolving drug alteplase, widely used as a thrombolytic treatment for acute ischemic stroke and certain types of heart attack and pulmonary embolism.
-
E.
Tylenol
Tylenol is a widely used over-the-counter pain reliever and fever reducer whose active ingredient is acetaminophen (paracetamol).
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: oseltamivir Target entity description: Oseltamivir is an oral antiviral medication (commonly known by the brand name Tamiflu) used to treat and prevent influenza, including pandemic strains such as 2009 H1N1.
-
A.
Leqembi
Leqembi is an Alzheimer’s disease drug (lecanemab) that targets amyloid-beta plaques to slow cognitive decline in early-stage patients.
-
B.
Vumerity
Vumerity is an oral prescription medication used to treat relapsing forms of multiple sclerosis in adults.
-
C.
Plegridy
Plegridy is a pegylated interferon beta-1a medication used to treat relapsing forms of multiple sclerosis.
-
D.
Activase
Activase is a brand-name form of the clot-dissolving drug alteplase, widely used as a thrombolytic treatment for acute ischemic stroke and certain types of heart attack and pulmonary embolism.
-
E.
Tylenol
Tylenol is a widely used over-the-counter pain reliever and fever reducer whose active ingredient is acetaminophen (paracetamol).
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
antiviral drug
ⓘ
neuraminidase inhibitor ⓘ prodrug ⓘ small molecule ⓘ |
| approvedBy |
U.S. Food and Drug Administration
ⓘ
linked to:
Food and Drug Administration
|
| approvedForUseIn |
adults
ⓘ
children ⓘ |
| belongsToPharmacologicClass | neuraminidase inhibitors ⓘ |
| contraindicatedIn | patients with known hypersensitivity to oseltamivir ⓘ |
| developedBy |
Gilead Sciences
ⓘ
linked to:
Gilead Sciences (board member)
|
| hasAdministrationSchedule |
once daily for prophylaxis
ⓘ
twice daily for treatment ⓘ |
| hasATCCode | J05AH02 ⓘ |
| hasBioavailability | high oral bioavailability ⓘ |
| hasBlackBoxWarning | none (as of 2024, US) ⓘ |
| hasBrandName |
Tamiflu
ⓘ
linked to:
oseltamivir
|
| hasChemicalFormula | C16H28N2O4 ⓘ |
| hasCommonSideEffect |
abdominal pain
ⓘ
diarrhea ⓘ headache ⓘ nausea ⓘ vomiting ⓘ |
| hasDrugClass |
anti-influenza agent
ⓘ
antiviral for systemic use ⓘ |
| hasEliminationRoute | renal excretion ⓘ |
| hasIndication |
post-exposure prophylaxis of influenza
ⓘ
uncomplicated acute illness due to influenza infection ⓘ |
| hasLegalStatus | prescription only ⓘ |
| hasMechanismOfAction |
inhibition of viral neuraminidase
ⓘ
prevents release of new influenza virions from infected cells ⓘ |
| hasPotentialAdverseEffect | neuropsychiatric events ⓘ |
| hasPregnancyCategory | C (US, historical classification) ⓘ |
| hasRouteOfAdministration |
oral
ⓘ
oral capsule ⓘ oral suspension ⓘ |
| hasTarget | influenza virus neuraminidase ⓘ |
| isListedOn | World Health Organization Model List of Essential Medicines ⓘ |
| isMostEffectiveWhen | started within 48 hours of onset of influenza symptoms ⓘ |
| isProdrugOf | oseltamivir carboxylate ⓘ |
| marketedBy | Roche ⓘ |
| usedFor |
prevention of influenza
ⓘ
prophylaxis of influenza A ⓘ prophylaxis of influenza B ⓘ treatment of 2009 H1N1 influenza ⓘ treatment of influenza ⓘ treatment of influenza A ⓘ treatment of influenza B ⓘ |
| wasWidelyUsedDuring | 2009 H1N1 influenza pandemic ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: oseltamivir Description of subject: Oseltamivir is an oral antiviral medication (commonly known by the brand name Tamiflu) used to treat and prevent influenza, including pandemic strains such as 2009 H1N1.
Referenced by (5)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: oseltamivir
linked to: oseltamivir