Gemin6

E561088

Gemin6 is a component of the SMN (survival motor neuron) complex involved in the assembly and maturation of small nuclear ribonucleoproteins essential for pre-mRNA splicing.

All labels observed (5)

Label Occurrences
Gemin6 canonical 7
Gemin proteins 2
GEMIN6 gene 1

How this entity was disambiguated

Statements (43)

Predicate Object
instanceOf SMN complex component ⓘ
protein ⓘ
protein-coding gene ⓘ
associatedWith SMN complex ⓘ
motor neuron function ⓘ
spinal muscular atrophy pathway ⓘ
binds Gemin7 ⓘ
SMN1 protein ⓘ
linked to: SMN1 gene
biologicalProcess RNA splicing ⓘ
U snRNP assembly ⓘ
mRNA processing ⓘ
cellularComponent SMN complex ⓘ
cytoplasmic ribonucleoprotein granule ⓘ
nuclear body ⓘ
conservedIn metazoans ⓘ
vertebrates ⓘ
encodedBy GEMIN6 gene ⓘ
linked to: Gemin6
encodes Gemin6 ⓘ
expressedIn human cells ⓘ
neuronal tissue ⓘ
formsComplexWith Gemin2 ⓘ
Gemin3 ⓘ
Gemin4 ⓘ
Gemin5 ⓘ
Gemin7 ⓘ
SMN1 protein ⓘ
linked to: SMN1 gene
involvedIn spliceosome biogenesis ⓘ
locatedIn Cajal bodies ⓘ
Gems ⓘ
cytoplasm ⓘ
nucleus ⓘ
locatedOn human chromosome 2 ⓘ
molecularFunction RNA binding ⓘ
protein binding ⓘ
orthologOf mouse Gemin6 ⓘ
zebrafish Gemin6 ⓘ
linked to: Gemin6
participatesIn pre-mRNA splicing ⓘ
small nuclear ribonucleoprotein assembly ⓘ
snRNP maturation ⓘ
partOf SMN complex ⓘ
requiredFor efficient snRNP assembly ⓘ
proper spliceosome function ⓘ
taxon Homo sapiens ⓘ

How these facts were elicited

Referenced by (12)

Full triples — surface form annotated when it differs from this entity's canonical label.

Survival motor neuron protein → formsComplexWith → Gemin6 ⓘ
subject linked to: survival motor neuron protein
gems (Gemini of Cajal bodies) → contains → Gemin proteins ⓘ
linked to: Gemin6
Gemin4 → inComplexWith → Gemin6 ⓘ
Gemin5 → interactsWith → Gemin6 ⓘ
Gemin6 → orthologOf → zebrafish Gemin6 ⓘ
linked to: Gemin6
Gemin6 → encodedBy → GEMIN6 gene ⓘ
linked to: Gemin6
GEMIN6 gene → encodes → Gemin6 ⓘ
subject linked to: Gemin6
Gemin8 → binds → Gemin6 ⓘ
Gemin8 → associatedWithComplex → Gemin6–Gemin7–Gemin8 subcomplex ⓘ
linked to: Gemin6
Sm proteins → interactsWith → Gemin proteins ⓘ
linked to: Gemin6
SMN complex → hasComponent → Gemin6 ⓘ