Axura
E494107
Axura is a brand-name medication containing memantine, commonly prescribed to treat moderate to severe Alzheimer's disease by helping regulate abnormal activity of the neurotransmitter glutamate in the brain.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Axura canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T5114929 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Axura Context triple: [Memantine, isMarketedUnderBrandName, Axura]
-
A.
Yasa'ur
Yasa'ur was a Mongol prince and military leader who played a significant role in the politics and conflicts of the Chagatai Khanate during the early 14th century.
-
B.
Aternus
Aternus is an ancient river in central Italy historically associated with the territory of the Marrucini people.
-
C.
El-Aurian
El-Aurians are a long-lived, empathic listener species in the Star Trek universe, best known through the character Guinan and their near-extinction by the Borg.
-
D.
Aezani
Aezani was an ancient Phrygian city in modern-day Turkey, notable for its well-preserved Roman ruins including a major temple to Zeus and other public buildings.
-
E.
Arkasa
Arkasa is a coastal village on the Greek island of Karpathos, known for its scenic beaches and nearby ancient archaeological sites.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Axura Target entity description: Axura is a brand-name medication containing memantine, commonly prescribed to treat moderate to severe Alzheimer's disease by helping regulate abnormal activity of the neurotransmitter glutamate in the brain.
-
A.
Yasa'ur
Yasa'ur was a Mongol prince and military leader who played a significant role in the politics and conflicts of the Chagatai Khanate during the early 14th century.
-
B.
Aternus
Aternus is an ancient river in central Italy historically associated with the territory of the Marrucini people.
-
C.
El-Aurian
El-Aurians are a long-lived, empathic listener species in the Star Trek universe, best known through the character Guinan and their near-extinction by the Borg.
-
D.
Aezani
Aezani was an ancient Phrygian city in modern-day Turkey, notable for its well-preserved Roman ruins including a major temple to Zeus and other public buildings.
-
E.
Arkasa
Arkasa is a coastal village on the Greek island of Karpathos, known for its scenic beaches and nearby ancient archaeological sites.
- F. None of above. chosen
Statements (40)
| Predicate | Object |
|---|---|
| instanceOf |
brand-name medication
ⓘ
memantine-containing medicine ⓘ |
| actsOn | central nervous system ⓘ |
| affects | glutamatergic neurotransmission ⓘ |
| commonAdverseEffect |
constipation
ⓘ
dizziness ⓘ headache ⓘ hypertension ⓘ somnolence ⓘ |
| contraindication | hypersensitivity to memantine ⓘ |
| drugClass | anti-dementia drug ⓘ |
| elimination | primarily renal ⓘ |
| formulation |
film-coated tablet
ⓘ
oral solution ⓘ |
| hasActiveIngredient | memantine ⓘ |
| hasDosageForm |
10 mg tablet
ⓘ
20 mg tablet ⓘ |
| hasGenericEquivalent | memantine ⓘ |
| indication |
moderate Alzheimer's disease
ⓘ
severe Alzheimer's disease ⓘ |
| intendedUse | long-term treatment ⓘ |
| mechanismOfAction |
blocks NMDA receptors
ⓘ
reduces pathological effects of excess glutamate ⓘ regulates abnormal glutamatergic neurotransmission ⓘ |
| metabolism | partially hepatic ⓘ |
| onsetOfAction | gradual ⓘ |
| pharmacologicalClass | NMDA receptor antagonist ⓘ |
| pregnancyCategory | use only if clearly needed ⓘ |
| regulates | glutamate activity ⓘ |
| regulatoryStatus | prescription-only medicine ⓘ |
| requiresPrescription | true ⓘ |
| routeOfAdministration | oral ⓘ |
| targetPopulation |
adult patients
ⓘ
elderly patients ⓘ |
| therapeuticArea |
neurology
ⓘ
psychiatry ⓘ |
| treats | Alzheimer's disease ⓘ |
| usedAs |
adjunct therapy for Alzheimer's disease
ⓘ
monotherapy for Alzheimer's disease ⓘ |
| usedIn | treatment of dementia in Alzheimer's disease ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Axura Description of subject: Axura is a brand-name medication containing memantine, commonly prescribed to treat moderate to severe Alzheimer's disease by helping regulate abnormal activity of the neurotransmitter glutamate in the brain.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject linked to:
memantine