Lipitor
E474929
Lipitor is a widely prescribed statin medication used to lower cholesterol and reduce the risk of cardiovascular disease.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Lipitor canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T4850376 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Lipitor Context triple: [Pfizer, developed, Lipitor]
-
A.
Zetia
Zetia is a prescription cholesterol-lowering medication (generic name ezetimibe) that reduces intestinal absorption of cholesterol and is marketed by Merck & Co.
-
B.
Lamotrek
Lamotrek is a small atoll in the Federated States of Micronesia known for its traditional seafaring culture and navigational expertise.
-
C.
Motrin
Motrin is a widely used over-the-counter ibuprofen pain reliever and fever reducer medication.
-
D.
Xarelto
Xarelto is a widely used prescription anticoagulant (blood thinner) that helps prevent and treat blood clots and reduce the risk of stroke in certain patients.
-
E.
Prozac
Prozac is a widely prescribed antidepressant medication (fluoxetine) used to treat major depressive disorder, anxiety disorders, and certain other mental health conditions.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Lipitor Target entity description: Lipitor is a widely prescribed statin medication used to lower cholesterol and reduce the risk of cardiovascular disease.
-
A.
Zetia
Zetia is a prescription cholesterol-lowering medication (generic name ezetimibe) that reduces intestinal absorption of cholesterol and is marketed by Merck & Co.
-
B.
Lamotrek
Lamotrek is a small atoll in the Federated States of Micronesia known for its traditional seafaring culture and navigational expertise.
-
C.
Motrin
Motrin is a widely used over-the-counter ibuprofen pain reliever and fever reducer medication.
-
D.
Xarelto
Xarelto is a widely used prescription anticoagulant (blood thinner) that helps prevent and treat blood clots and reduce the risk of stroke in certain patients.
-
E.
Prozac
Prozac is a widely prescribed antidepressant medication (fluoxetine) used to treat major depressive disorder, anxiety disorders, and certain other mental health conditions.
- F. None of above. chosen
Statements (51)
| Predicate | Object |
|---|---|
| instanceOf |
brand name drug
ⓘ
pharmaceutical drug ⓘ statin medication ⓘ |
| approvalBy |
U.S. Food and Drug Administration
ⓘ
linked to:
Food and Drug Administration
|
| ATCCode | C10AA05 ⓘ |
| blackBoxWarning | contraindicated in pregnancy and lactation ⓘ |
| chemicalFormula | C33H35FN2O5 ⓘ |
| commonAdverseEffect |
diarrhea
ⓘ
dyspepsia ⓘ myalgia ⓘ nausea ⓘ |
| contraindication |
active liver disease
ⓘ
breastfeeding ⓘ pregnancy ⓘ unexplained persistent elevations of liver transaminases ⓘ |
| countryOfOrigin |
United States
ⓘ
linked to:
United States of America
|
| developer | Pfizer ⓘ |
| dosageForm | oral tablet ⓘ |
| drugClass |
HMG-CoA reductase inhibitor
ⓘ
statin ⓘ |
| effect |
lowers LDL cholesterol
ⓘ
lowers total cholesterol ⓘ lowers triglycerides ⓘ modestly increases HDL cholesterol ⓘ |
| FDAApprovalYear | 1996 ⓘ |
| genericName | atorvastatin ⓘ |
| halfLife | approximately 14 hours ⓘ |
| hasGeneric | atorvastatin generic formulations ⓘ |
| indication |
hypercholesterolemia
ⓘ
mixed dyslipidemia ⓘ prevention of myocardial infarction ⓘ prevention of stroke ⓘ primary prevention of cardiovascular disease ⓘ secondary prevention of cardiovascular disease ⓘ treatment of heterozygous familial hypercholesterolemia ⓘ treatment of homozygous familial hypercholesterolemia ⓘ |
| legalStatusEU | prescription only ⓘ |
| legalStatusUS | prescription only ⓘ |
| manufacturer | Pfizer ⓘ |
| mechanismOfAction | inhibits HMG-CoA reductase ⓘ |
| metabolism | CYP3A4 ⓘ |
| patentStatus | patent expired ⓘ |
| pregnancyCategory | contraindicated in pregnancy ⓘ |
| proteinBinding | high ⓘ |
| routeOfAdministration | oral ⓘ |
| seriousAdverseEffect |
hepatotoxicity
ⓘ
myopathy ⓘ rhabdomyolysis ⓘ |
| target | HMG-CoA reductase enzyme ⓘ |
| therapeuticArea | cardiovascular disease ⓘ |
| typicalDoseRange | 10–80 mg once daily ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Lipitor Description of subject: Lipitor is a widely prescribed statin medication used to lower cholesterol and reduce the risk of cardiovascular disease.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.