neutral theory of population genetics
E473474
The neutral theory of population genetics is an evolutionary framework proposing that most genetic variation and molecular changes in populations are governed by random genetic drift of selectively neutral mutations rather than by natural selection.
All labels observed (2)
| Label | Occurrences |
|---|---|
| neutral theory of population genetics canonical | 1 |
| 中立進化説 | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T4847733 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: neutral theory of population genetics Context triple: [Unified Neutral Theory of Biodiversity and Biogeography, basedOn, neutral theory of population genetics]
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A.
Evolution in Mendelian Populations
"Evolution in Mendelian Populations" is a foundational 1931 paper by Sewall Wright that introduced key concepts of population genetics, including genetic drift, inbreeding, and the shifting balance theory of evolution.
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B.
Hardy–Weinberg principle
The Hardy–Weinberg principle is a fundamental concept in population genetics that describes how allele and genotype frequencies remain constant from generation to generation in an idealized, non-evolving population.
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C.
shifting balance theory
Shifting balance theory is an evolutionary framework proposed by Sewall Wright that explains how genetic drift, selection, and gene flow interact across subdivided populations to drive adaptive evolution.
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D.
Unified Neutral Theory of Biodiversity and Biogeography
Unified Neutral Theory of Biodiversity and Biogeography is an influential ecological theory proposing that biodiversity patterns and species abundances can be explained by assuming ecological equivalence among individuals regardless of species.
-
E.
Evolution and the Genetics of Populations
Evolution and the Genetics of Populations is a foundational multi-volume work in population genetics that systematically presents Sewall Wright’s theories on genetic drift, inbreeding, selection, and the evolutionary process.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: neutral theory of population genetics Target entity description: The neutral theory of population genetics is an evolutionary framework proposing that most genetic variation and molecular changes in populations are governed by random genetic drift of selectively neutral mutations rather than by natural selection.
-
A.
Evolution in Mendelian Populations
"Evolution in Mendelian Populations" is a foundational 1931 paper by Sewall Wright that introduced key concepts of population genetics, including genetic drift, inbreeding, and the shifting balance theory of evolution.
-
B.
Hardy–Weinberg principle
The Hardy–Weinberg principle is a fundamental concept in population genetics that describes how allele and genotype frequencies remain constant from generation to generation in an idealized, non-evolving population.
-
C.
shifting balance theory
Shifting balance theory is an evolutionary framework proposed by Sewall Wright that explains how genetic drift, selection, and gene flow interact across subdivided populations to drive adaptive evolution.
-
D.
Unified Neutral Theory of Biodiversity and Biogeography
Unified Neutral Theory of Biodiversity and Biogeography is an influential ecological theory proposing that biodiversity patterns and species abundances can be explained by assuming ecological equivalence among individuals regardless of species.
-
E.
Evolution and the Genetics of Populations
Evolution and the Genetics of Populations is a foundational multi-volume work in population genetics that systematically presents Sewall Wright’s theories on genetic drift, inbreeding, selection, and the evolutionary process.
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
evolutionary theory
ⓘ
scientific theory ⓘ theory in population genetics ⓘ |
| addresses |
molecular evolution
ⓘ
polymorphism within populations ⓘ |
| alsoKnownAs | neutral theory of molecular evolution ⓘ |
| appliesTo |
many protein-coding sequence changes
ⓘ
noncoding DNA variation ⓘ synonymous substitutions ⓘ |
| assumes |
effective population size influences the fate of neutral mutations
ⓘ
many mutations have no effect on organismal fitness ⓘ |
| contrastsWith |
adaptive evolutionism at the molecular level
ⓘ
selectionist theory of molecular evolution ⓘ |
| coreClaim |
most evolutionary changes at the molecular level are caused by random genetic drift of selectively neutral mutations
ⓘ
most standing genetic variation within populations is selectively neutral or nearly neutral ⓘ |
| criticizedFor | underestimating the role of adaptive evolution at the molecular level ⓘ |
| downplaysProcess | positive natural selection ⓘ |
| emphasizesProcess |
genetic drift
ⓘ
mutation ⓘ |
| extendedBy | nearly neutral theory of molecular evolution ⓘ |
| field |
evolutionary biology
ⓘ
population genetics ⓘ |
| influenced |
development of coalescent theory
ⓘ
interpretation of DNA sequence variation ⓘ molecular population genetics ⓘ |
| predicts |
heterozygosity depends on effective population size and neutral mutation rate
ⓘ
molecular clock-like constancy of substitution rates over time ⓘ most fixed differences between species at the molecular level are selectively neutral ⓘ rate of neutral molecular evolution equals neutral mutation rate ⓘ |
| proposedBy | Motoo Kimura ⓘ |
| providesModelFor | expected site frequency spectrum under neutrality ⓘ |
| providesNullModelFor |
Hudson–Kreitman–Aguadé test
ⓘ
McDonald–Kreitman test ⓘ Tajima's D ⓘ tests of natural selection ⓘ |
| publicationAuthor | Motoo Kimura ⓘ |
| publicationYear | 1983 ⓘ |
| publishedIn | The Neutral Theory of Molecular Evolution ⓘ |
| relatedConcept |
coalescent process
ⓘ
effective population size ⓘ genetic drift ⓘ molecular clock ⓘ selectively neutral mutation ⓘ |
| supportsView | much molecular evolution is non-adaptive ⓘ |
| timePeriod | late 1960s ⓘ |
| usedIn |
detecting deviations from neutrality as evidence of selection
ⓘ
estimating effective population size from neutral markers ⓘ inferring demographic history from neutral loci ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: neutral theory of population genetics Description of subject: The neutral theory of population genetics is an evolutionary framework proposing that most genetic variation and molecular changes in populations are governed by random genetic drift of selectively neutral mutations rather than by natural selection.
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.