Ambien

E411218

Ambien is a widely prescribed sedative-hypnotic medication (generic name zolpidem) used short-term to treat insomnia by helping people fall asleep more quickly.

All labels observed (3)

Label Occurrences
Ambien canonical 1
Ambien CR 1
zolpidem 1

How this entity was disambiguated

Statements (48)

Predicate Object
instanceOf brand name drug ⓘ
medication ⓘ
sedative-hypnotic drug ⓘ
actsOn GABA-A receptor ⓘ
administrationInstruction should be taken immediately before bedtime ⓘ
should be taken only when able to stay in bed for a full night ⓘ
boxedWarningUS complex sleep behaviors resulting in serious injuries or death ⓘ
brandVariant Ambien CR ⓘ
linked to: Ambien
commonSideEffect dizziness ⓘ
drowsiness ⓘ
headache ⓘ
nausea ⓘ
contraindication known hypersensitivity to zolpidem ⓘ
developer Sanofi ⓘ
dosageForm extended-release tablet ⓘ
immediate-release tablet ⓘ
firstApprovalAgency U.S. Food and Drug Administration ⓘ
firstApprovalRegion United States ⓘ
halfLife approximately 2 to 3 hours in healthy adults ⓘ
hasActiveIngredient zolpidem tartrate ⓘ
hasGenericName zolpidem ⓘ
linked to: Ambien
indication short-term treatment of insomnia ⓘ
legalStatusUS Schedule IV controlled substance ⓘ
mechanismOfAction enhances GABA-mediated neuronal inhibition ⓘ
metabolism hepatic ⓘ
metabolizedBy CYP3A4 ⓘ
onsetOfAction rapid ⓘ
pharmacologicalClass imidazopyridine derivative ⓘ
non-benzodiazepine hypnotic ⓘ
pregnancyCategoryUS C ⓘ
primaryEffect helps people fall asleep more quickly ⓘ
regulatoryStatus prescription-only medication ⓘ
risk dependence ⓘ
tolerance ⓘ
withdrawal symptoms ⓘ
routeOfAdministration oral ⓘ
selectivity preferentially binds GABA-A receptors containing the alpha-1 subunit ⓘ
seriousSideEffect abnormal thinking and behavioral changes ⓘ
complex sleep behaviors ⓘ
sleep-driving ⓘ
sleepwalking ⓘ
therapeuticArea sleep medicine ⓘ
treatmentDuration recommended for short-term use ⓘ
treats insomnia ⓘ
typicalUse taken at bedtime ⓘ
warning avoid use with alcohol ⓘ
caution in elderly patients ⓘ
caution in patients with respiratory impairment ⓘ

How these facts were elicited

Referenced by (3)

Full triples — surface form annotated when it differs from this entity's canonical label.

Ambien → hasGenericName → zolpidem ⓘ
linked to: Ambien
Ambien → brandVariant → Ambien CR ⓘ
linked to: Ambien