albendazole
E396236
Albendazole is a broad-spectrum anthelmintic medication commonly used to treat a variety of parasitic worm infections in humans.
All labels observed (2)
| Label | Occurrences |
|---|---|
| albendazole canonical | 3 |
| Albenza | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T3872171 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: albendazole Context triple: [Ascaris lumbricoides, treatment, albendazole]
-
A.
Plaxtol
Plaxtol is a small rural village and civil parish in Kent, England, known for its historic buildings and surrounding countryside.
-
B.
Wormit
Wormit is a small village in Fife, Scotland, situated on the south bank of the River Tay near the Tay Rail Bridge.
-
C.
Opekta
Opekta was a German-Dutch company that produced and sold pectin-based gelling agents for making jam, notably managed in its Amsterdam branch by Anne Frank’s father, Otto Frank.
-
D.
Auscitain
An Auscitain is a resident or native of Auch, a historic town in the Occitanie region of southwestern France.
-
E.
Ascaris lumbricoides
Ascaris lumbricoides is a large parasitic roundworm that infects the human intestine and is a common cause of ascariasis worldwide.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: albendazole Target entity description: Albendazole is a broad-spectrum anthelmintic medication commonly used to treat a variety of parasitic worm infections in humans.
-
A.
Plaxtol
Plaxtol is a small rural village and civil parish in Kent, England, known for its historic buildings and surrounding countryside.
-
B.
Wormit
Wormit is a small village in Fife, Scotland, situated on the south bank of the River Tay near the Tay Rail Bridge.
-
C.
Opekta
Opekta was a German-Dutch company that produced and sold pectin-based gelling agents for making jam, notably managed in its Amsterdam branch by Anne Frank’s father, Otto Frank.
-
D.
Auscitain
An Auscitain is a resident or native of Auch, a historic town in the Occitanie region of southwestern France.
-
E.
Ascaris lumbricoides
Ascaris lumbricoides is a large parasitic roundworm that infects the human intestine and is a common cause of ascariasis worldwide.
- F. None of above. chosen
Statements (64)
| Predicate | Object |
|---|---|
| instanceOf |
anthelmintic drug
ⓘ
benzimidazole derivative ⓘ pharmaceutical drug ⓘ |
| belongsToDrugClass | broad-spectrum anthelmintics ⓘ |
| bioavailabilityIncreasesWith | fatty meal ⓘ |
| hasATCCode | P02CA03 ⓘ |
| hasBioavailability | low oral bioavailability ⓘ |
| hasCASNumber | 54965-21-8 ⓘ |
| hasChemicalFormula | C12H15N3O2S ⓘ |
| hasCommonAdverseEffect |
abdominal pain
ⓘ
dizziness ⓘ headache ⓘ nausea ⓘ vomiting ⓘ |
| hasDrugBankID | DB00518 ⓘ |
| hasHalfLife | 8–12 hours for albendazole sulfoxide ⓘ |
| hasIUPACName | methyl N-[6-(propylthio)-1H-benzimidazol-2-yl]carbamate ⓘ |
| hasLegalStatus | prescription-only in many countries ⓘ |
| hasMechanismOfAction |
disrupts microtubule-dependent glucose uptake in parasites
ⓘ
inhibits tubulin polymerization in parasites ⓘ |
| hasMetabolite |
albendazole sulfone
ⓘ
albendazole sulfoxide ⓘ |
| hasMolarMass | 265.33 g/mol ⓘ |
| hasPregnancyCategory | Category C (US, historical classification) ⓘ |
| hasPubChemCID | 2082 ⓘ |
| hasRouteOfAdministration | oral ⓘ |
| hasSeriousAdverseEffect |
bone marrow suppression
ⓘ
hepatotoxicity ⓘ |
| hasSynonym |
Albenza
ⓘ
linked to:
albendazole
Eskazole ⓘ albendazol ⓘ |
| hasUNII | F4216019LN ⓘ |
| isAvailableAs |
chewable tablet
ⓘ
oral suspension ⓘ tablet ⓘ |
| isContraindicatedIn |
known hypersensitivity to benzimidazoles
ⓘ
pregnancy (first trimester) ⓘ |
| isExcretedBy |
biliary route
ⓘ
renal route ⓘ |
| isListedOn | World Health Organization Model List of Essential Medicines ⓘ |
| isMetabolizedIn | liver ⓘ |
| isProdrugOf | albendazole sulfoxide ⓘ |
| isUsedIn |
human medicine
ⓘ
veterinary medicine ⓘ |
| resultsIn |
death of susceptible helminths
ⓘ
depletion of glycogen stores in parasites ⓘ |
| targetsOrganism | parasitic worms ⓘ |
| treats |
ascariasis
ⓘ
capillariasis ⓘ cutaneous larva migrans ⓘ echinococcosis ⓘ enterobiasis ⓘ giardiasis ⓘ gnathostomiasis ⓘ hookworm infection ⓘ hydatid disease ⓘ hymenolepiasis ⓘ neurocysticercosis ⓘ strongyloidiasis ⓘ taeniasis ⓘ toxocariasis ⓘ trichinellosis ⓘ trichuriasis ⓘ |
| wasApprovedIn | 1980s ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: albendazole Description of subject: Albendazole is a broad-spectrum anthelmintic medication commonly used to treat a variety of parasitic worm infections in humans.
Referenced by (4)
Full triples — surface form annotated when it differs from this entity's canonical label.