Fampyra
E28893
Fampyra is a prescription medication (prolonged-release fampridine) used to improve walking in adults with multiple sclerosis.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Fampyra canonical | 3 |
How this entity was disambiguated
This entity first appeared as the object of triple T195376 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Fampyra Context triple: [Biogen, hasProduct, Fampyra]
-
A.
Wiphala
The Wiphala is a multicolored, checkered flag representing the Indigenous peoples of the Andes and widely recognized as a symbol of Indigenous identity and plurinationalism in Bolivia.
-
B.
Beni
Beni is a sparsely populated, largely Amazonian department in northeastern Bolivia known for its tropical lowlands, cattle ranching, and rich indigenous cultures.
-
C.
Kalorama
Kalorama is an affluent, historic residential neighborhood in Northwest Washington, D.C., known for its embassies, stately mansions, and prominent political residents.
-
D.
Taphus
Taphus was the original name of the town that later became Charlotte Amalie, the capital of the U.S. Virgin Islands.
-
E.
Anif
Anif is a small Austrian municipality near Salzburg, known for its historic castle and as a residence of notable figures.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Fampyra Target entity description: Fampyra is a prescription medication (prolonged-release fampridine) used to improve walking in adults with multiple sclerosis.
-
A.
Wiphala
The Wiphala is a multicolored, checkered flag representing the Indigenous peoples of the Andes and widely recognized as a symbol of Indigenous identity and plurinationalism in Bolivia.
-
B.
Beni
Beni is a sparsely populated, largely Amazonian department in northeastern Bolivia known for its tropical lowlands, cattle ranching, and rich indigenous cultures.
-
C.
Kalorama
Kalorama is an affluent, historic residential neighborhood in Northwest Washington, D.C., known for its embassies, stately mansions, and prominent political residents.
-
D.
Taphus
Taphus was the original name of the town that later became Charlotte Amalie, the capital of the U.S. Virgin Islands.
-
E.
Anif
Anif is a small Austrian municipality near Salzburg, known for its historic castle and as a residence of notable figures.
- F. None of above. chosen
Statements (45)
| Predicate | Object |
|---|---|
| instanceOf |
brand name drug
ⓘ
medicinal product ⓘ |
| actsOn | central nervous system ⓘ |
| approvalYear | 2011 ⓘ |
| approvedBy | European Medicines Agency ⓘ |
| commonAdverseEffect |
dizziness
ⓘ
headache ⓘ insomnia ⓘ nausea ⓘ urinary tract infection ⓘ |
| containsExcipient | lactose ⓘ |
| contraindicatedIn |
history of seizures
ⓘ
moderate or severe renal impairment ⓘ |
| developedBy |
Biogen Idec
ⓘ
linked to:
Biogen
|
| dosingInterval | every 12 hours ⓘ |
| hasActiveIngredient |
4-aminopyridine
ⓘ
fampridine ⓘ |
| hasApprovalRegion | European Union ⓘ |
| hasATCCode | N07XX07 ⓘ |
| hasDosageForm | prolonged-release tablet ⓘ |
| hasInternationalNonproprietaryName | fampridine ⓘ |
| hasRouteOfAdministration | oral ⓘ |
| hasStrength | 10 mg prolonged-release tablet ⓘ |
| hasTradeName | Fampyra ⓘ |
| improvementAssessmentTool | Timed 25-Foot Walk test ⓘ |
| improves |
walking ability in multiple sclerosis patients
ⓘ
walking speed in multiple sclerosis patients ⓘ |
| indicatedFor |
impaired walking in multiple sclerosis
ⓘ
multiple sclerosis ⓘ |
| intendedPopulation | adults ⓘ |
| isExtendedReleaseFormulationOf | fampridine ⓘ |
| legalStatusEU | prescription only medicine ⓘ |
| marketingAuthorisationHolder |
Biogen Netherlands B.V.
ⓘ
linked to:
Biogen
|
| mechanismOfAction |
blocks voltage-gated potassium channels
ⓘ
enhances conduction in demyelinated axons ⓘ |
| notIndicatedFor | patients under 18 years of age ⓘ |
| pharmacologicalClass | potassium channel blocker ⓘ |
| pregnancyCategory | use only if potential benefit justifies potential risk ⓘ |
| requires | prescription ⓘ |
| requiresMonitoring |
renal function
ⓘ
seizure risk ⓘ |
| riskManagementPlanRequiredBy | European Medicines Agency ⓘ |
| seriousAdverseEffect | seizure ⓘ |
| storageCondition | store below 25°C ⓘ |
| therapeuticArea | neurology ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Fampyra Description of subject: Fampyra is a prescription medication (prolonged-release fampridine) used to improve walking in adults with multiple sclerosis.
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.