Avsola
E242411
Avsola is a biosimilar monoclonal antibody to infliximab used to treat various autoimmune inflammatory conditions.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Avsola canonical | 2 |
How this entity was disambiguated
This entity first appeared as the object of triple T2190629 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Avsola Context triple: [Remicade, hasBiosimilar, Avsola]
-
A.
Veltro
Veltro is the nickname of the Macchi C.205, an Italian World War II fighter aircraft renowned for its speed and agility.
-
B.
Avusy
Avusy is a small rural municipality located in the canton of Geneva in southwestern Switzerland, near the French border.
-
C.
Nobsa
Nobsa is a Colombian town known for its traditional wool textiles and crafts, located in the Boyacá Department.
-
D.
Nolano
Nolano is the Italian demonym for a person from the town of Nola in the Campania region of southern Italy.
-
E.
Yeola
Yeola is a town in the Nashik district of Maharashtra, India, known historically as the birthplace of the Indian freedom fighter Tatya Tope.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Avsola Target entity description: Avsola is a biosimilar monoclonal antibody to infliximab used to treat various autoimmune inflammatory conditions.
-
A.
Veltro
Veltro is the nickname of the Macchi C.205, an Italian World War II fighter aircraft renowned for its speed and agility.
-
B.
Avusy
Avusy is a small rural municipality located in the canton of Geneva in southwestern Switzerland, near the French border.
-
C.
Nobsa
Nobsa is a Colombian town known for its traditional wool textiles and crafts, located in the Boyacá Department.
-
D.
Nolano
Nolano is the Italian demonym for a person from the town of Nola in the Campania region of southern Italy.
-
E.
Yeola
Yeola is a town in the Nashik district of Maharashtra, India, known historically as the birthplace of the Indian freedom fighter Tatya Tope.
- F. None of above. chosen
Statements (47)
| Predicate | Object |
|---|---|
| instanceOf |
biologic medicinal product
ⓘ
biosimilar medicine ⓘ monoclonal antibody ⓘ tumor necrosis factor inhibitor ⓘ |
| hasAdverseEffect |
infusion-related reaction
ⓘ
malignancy risk ⓘ reactivation of latent tuberculosis ⓘ serious infections ⓘ |
| hasATCClass | L04AB02 ⓘ |
| hasBlackBoxWarning |
malignancy
ⓘ
serious infections ⓘ |
| hasBrandName | Avsola ⓘ |
| hasContraindication |
active tuberculosis
ⓘ
severe infections ⓘ |
| hasDosageForm |
concentrate for solution for infusion
ⓘ
solution for infusion ⓘ |
| hasEffect |
reduces inflammation
ⓘ
suppresses immune response ⓘ |
| hasIndication |
active ankylosing spondylitis
ⓘ
active psoriatic arthritis ⓘ fistulizing Crohn's disease ⓘ moderate to severe Crohn's disease ⓘ moderate to severe plaque psoriasis ⓘ moderate to severe rheumatoid arthritis ⓘ moderate to severe ulcerative colitis ⓘ |
| hasInternationalNonproprietaryName | infliximab-axxq ⓘ |
| hasManufacturer | Amgen ⓘ |
| hasMechanismOfAction |
binds to soluble TNF-alpha
ⓘ
binds to transmembrane TNF-alpha ⓘ neutralizes TNF-alpha biological activity ⓘ |
| hasOriginatorReferenceProduct | Remicade ⓘ |
| hasRegulatoryStatus |
approved in the European Union
ⓘ
approved in the United States ⓘ |
| hasRouteOfAdministration | intravenous infusion ⓘ |
| isAdministeredBy | healthcare professional ⓘ |
| isAdministeredWith | intravenous infusion equipment ⓘ |
| isBiosimilarTo |
infliximab
ⓘ
linked to:
Remicade
|
| isUsedFor |
Crohn's disease
ⓘ
ankylosing spondylitis ⓘ plaque psoriasis ⓘ psoriatic arthritis ⓘ rheumatoid arthritis ⓘ ulcerative colitis ⓘ |
| requiresMonitoring |
hepatitis B virus reactivation
ⓘ
signs and symptoms of infection ⓘ tuberculosis status ⓘ |
| targets | tumor necrosis factor alpha ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Avsola Description of subject: Avsola is a biosimilar monoclonal antibody to infliximab used to treat various autoimmune inflammatory conditions.
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.