prefrontal cortex

E189286

The prefrontal cortex is the front part of the brain’s frontal lobes responsible for higher-order functions such as decision-making, attention, impulse control, and working memory.

All labels observed (10)

How this entity was disambiguated

Statements (64)

Predicate Object
instanceOf brain region ⓘ
cerebral cortex region ⓘ
borderedBy premotor cortex ⓘ
composedOf gray matter ⓘ
connectedTo amygdala ⓘ
basal ganglia ⓘ
hippocampus ⓘ
limbic system ⓘ
parietal cortex ⓘ
temporal cortex ⓘ
thalamus ⓘ
contains GABAergic interneurons ⓘ
pyramidal neurons ⓘ
damageAssociatedWith deficits in working memory ⓘ
executive dysfunction ⓘ
impaired decision-making ⓘ
personality changes ⓘ
poor impulse control ⓘ
developsUntil early adulthood ⓘ
dysfunctionAssociatedWith attention-deficit hyperactivity disorder ⓘ
bipolar disorder ⓘ
major depressive disorder ⓘ
obsessive-compulsive disorder ⓘ
schizophrenia ⓘ
substance use disorders ⓘ
hasSubregion dorsolateral prefrontal cortex ⓘ
linked to: prefrontal cortex

frontopolar cortex ⓘ
linked to: prefrontal cortex

orbitofrontal cortex ⓘ
linked to: prefrontal cortex

ventrolateral prefrontal cortex ⓘ
ventromedial prefrontal cortex ⓘ
linked to: prefrontal cortex
involvedIn attention ⓘ
attention shifting ⓘ
behavioral flexibility ⓘ
cognitive control ⓘ
decision-making ⓘ
emotion regulation ⓘ
executive functions ⓘ
goal-directed behavior ⓘ
impulse control ⓘ
inhibitory control ⓘ
moral judgment ⓘ
personality expression ⓘ
planning ⓘ
problem solving ⓘ
reasoning ⓘ
reward processing ⓘ
risk assessment ⓘ
social cognition ⓘ
working memory ⓘ
working memory maintenance ⓘ
working memory manipulation ⓘ
locatedIn anterior frontal lobe ⓘ
forebrain ⓘ
human brain ⓘ
mammalian brain ⓘ
maturesLateComparedTo sensory cortices ⓘ
partOf cerebrum ⓘ
frontal lobe ⓘ
suppliedBy anterior cerebral artery ⓘ
middle cerebral artery ⓘ
supports abstract thinking ⓘ
conscious control of behavior ⓘ
delayed gratification ⓘ
rule-based behavior ⓘ

How these facts were elicited

Referenced by (19)

Full triples — surface form annotated when it differs from this entity's canonical label.

Emotions → isRegulatedBy → Prefrontal cortex ⓘ
linked to: prefrontal cortex
prefrontal cortex → hasSubregion → dorsolateral prefrontal cortex ⓘ
linked to: prefrontal cortex
prefrontal cortex → hasSubregion → ventromedial prefrontal cortex ⓘ
linked to: prefrontal cortex
prefrontal cortex → hasSubregion → orbitofrontal cortex ⓘ
linked to: prefrontal cortex
prefrontal cortex → hasSubregion → frontopolar cortex ⓘ
linked to: prefrontal cortex
cerebral cortex → hasPart → prefrontal cortex ⓘ
premotor cortex → locatedPosteriorTo → prefrontal cortex ⓘ
premotor cortex → borderedAnteriorlyBy → prefrontal cortex ⓘ
Limbic system → hasPart → Ventromedial prefrontal cortex ⓘ
linked to: prefrontal cortex
Limbic system → hasPart → Orbitofrontal cortex ⓘ
linked to: prefrontal cortex
Limbic system → connectedTo → Prefrontal cortex ⓘ
linked to: prefrontal cortex
Amygdala → connectedTo → prefrontal cortex ⓘ
somatic marker hypothesis → neuralBasis → ventromedial prefrontal cortex ⓘ
linked to: prefrontal cortex
anterior cerebral artery → supplies → medial prefrontal cortex ⓘ
linked to: prefrontal cortex
Supplementary motor area → receivesInputFrom → prefrontal cortex ⓘ
subject linked to: SMA
subthalamic nucleus → connectedWith → prefrontal cortex ⓘ
progressive supranuclear palsy → affectsAnatomicalStructure → frontal cortex ⓘ
linked to: prefrontal cortex
Global Neuronal Workspace Theory of Consciousness → neuralBasisInvolves → prefrontal cortex ⓘ