Triple
T22717679
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Dupixent |
E561777
|
entity |
| Predicate | targetsMolecule |
P37016
|
FINISHED |
| Object |
interleukin-4 receptor alpha
Interleukin-4 receptor alpha is a key immune cell surface receptor subunit that mediates signaling of the cytokines IL-4 and IL-13, playing a central role in allergic inflammation and type 2 immune responses.
|
E1550587
|
NE FINISHED |
How this triple was built (4 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: interleukin-4 receptor alpha | Statement: [Dupixent, targetsMolecule, interleukin-4 receptor alpha]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: interleukin-4 receptor alpha Context triple: [Dupixent, targetsMolecule, interleukin-4 receptor alpha]
-
A.
interleukin-4
Interleukin-4 is an immune signaling cytokine that promotes B cell proliferation, differentiation, and antibody class switching, particularly toward IgE production.
-
B.
IL-17RA
IL-17RA is a cell surface receptor subunit that mediates signaling for interleukin-17 family cytokines, playing a key role in inflammatory and autoimmune responses.
-
C.
IL-64
IL-64 is a major east–west state highway in Illinois that runs from the Mississippi River through the Chicago metropolitan area.
-
D.
Janus kinase 1
Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
-
E.
IL-17A
IL-17A is a pro-inflammatory cytokine produced mainly by Th17 cells that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: interleukin-4 receptor alpha Triple: [Dupixent, targetsMolecule, interleukin-4 receptor alpha]
Generated description
Interleukin-4 receptor alpha is a key immune cell surface receptor subunit that mediates signaling of the cytokines IL-4 and IL-13, playing a central role in allergic inflammation and type 2 immune responses.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: interleukin-4 receptor alpha Target entity description: Interleukin-4 receptor alpha is a key immune cell surface receptor subunit that mediates signaling of the cytokines IL-4 and IL-13, playing a central role in allergic inflammation and type 2 immune responses.
-
A.
interleukin-4
Interleukin-4 is an immune signaling cytokine that promotes B cell proliferation, differentiation, and antibody class switching, particularly toward IgE production.
-
B.
IL-17RA
IL-17RA is a cell surface receptor subunit that mediates signaling for interleukin-17 family cytokines, playing a key role in inflammatory and autoimmune responses.
-
C.
IL-64
IL-64 is a major east–west state highway in Illinois that runs from the Mississippi River through the Chicago metropolitan area.
-
D.
Janus kinase 1
Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
-
E.
IL-17A
IL-17A is a pro-inflammatory cytokine produced mainly by Th17 cells that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2454fc984819088213b58ee87a002 |
completed | April 17, 2026, 2:35 p.m. |
| NER | Named-entity recognition | batch_69f1790ecbc48190926d16b20b674dbd |
completed | April 29, 2026, 3:20 a.m. |
| NED1 | Entity disambiguation (via context triple) | batch_6a0b7edf9c988190ba19b094f3232c87 |
completed | May 18, 2026, 9:04 p.m. |
| NEDg | Description generation | batch_6a0b8076dd848190b7ee7c745ddee3c5 |
completed | May 18, 2026, 9:11 p.m. |
| NED2 | Entity disambiguation (via description) | batch_6a0b819ebe90819088593ffcd70251b1 |
completed | May 18, 2026, 9:16 p.m. |
Created at: April 17, 2026, 3:19 p.m.