Triple

T22690578
Position Surface form Disambiguated ID Type / Status
Subject BTK E561038 entity
Predicate belongsToFamily P4276 FINISHED
Object Tec family kinases
Tec family kinases are a group of non-receptor tyrosine kinases involved in signaling pathways that regulate lymphocyte development, activation, and function.
E1549334 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Tec family kinases | Statement: [BTK, belongsToFamily, Tec family kinases]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: Tec family kinases
Context triple: [BTK, belongsToFamily, Tec family kinases]
  • A. Src family kinases
    Src family kinases are a group of non-receptor tyrosine kinases that regulate key cellular processes such as proliferation, differentiation, survival, and migration, and are often implicated in cancer and immune signaling.
  • B. epidermal growth factor receptor family
    The epidermal growth factor receptor family is a group of closely related receptor tyrosine kinases (including EGFR/HER1, HER2, HER3, and HER4) that regulate cell growth, survival, and differentiation and are key targets in cancer biology and therapy.
  • C. Cdc25 homolog Mih1
    Cdc25 homolog Mih1 is a yeast phosphatase that activates the cyclin-dependent kinase Cdc28 to promote entry into mitosis by removing inhibitory phosphorylations.
  • D. CDK6
    CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
  • E. Janus kinase 1
    Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Tec family kinases
Triple: [BTK, belongsToFamily, Tec family kinases]
Generated description
Tec family kinases are a group of non-receptor tyrosine kinases involved in signaling pathways that regulate lymphocyte development, activation, and function.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: Tec family kinases
Target entity description: Tec family kinases are a group of non-receptor tyrosine kinases involved in signaling pathways that regulate lymphocyte development, activation, and function.
  • A. Src family kinases
    Src family kinases are a group of non-receptor tyrosine kinases that regulate key cellular processes such as proliferation, differentiation, survival, and migration, and are often implicated in cancer and immune signaling.
  • B. epidermal growth factor receptor family
    The epidermal growth factor receptor family is a group of closely related receptor tyrosine kinases (including EGFR/HER1, HER2, HER3, and HER4) that regulate cell growth, survival, and differentiation and are key targets in cancer biology and therapy.
  • C. Cdc25 homolog Mih1
    Cdc25 homolog Mih1 is a yeast phosphatase that activates the cyclin-dependent kinase Cdc28 to promote entry into mitosis by removing inhibitory phosphorylations.
  • D. CDK6
    CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
  • E. Janus kinase 1
    Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69e2454d71b48190a1f80af9f82b6fcf completed April 17, 2026, 2:35 p.m.
NER Named-entity recognition batch_69f1789a1fd08190bce5fa0babe695d3 completed April 29, 2026, 3:18 a.m.
NED1 Entity disambiguation (via context triple) batch_6a0b73fa5a648190b90ba303d1fe2397 completed May 18, 2026, 8:18 p.m.
NEDg Description generation batch_6a0b7755eb048190ba1657a9a09bc24b completed May 18, 2026, 8:32 p.m.
NED2 Entity disambiguation (via description) batch_6a0b780c0a4c8190b51b50c1e0e1a114 completed May 18, 2026, 8:35 p.m.
Created at: April 17, 2026, 3:13 p.m.