Tec family kinases
E1549334
UNEXPLORED
Tec family kinases are a group of non-receptor tyrosine kinases involved in signaling pathways that regulate lymphocyte development, activation, and function.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Tec family kinases canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22690578 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Tec family kinases Context triple: [BTK, belongsToFamily, Tec family kinases]
-
A.
Src family kinases
Src family kinases are a group of non-receptor tyrosine kinases that regulate key cellular processes such as proliferation, differentiation, survival, and migration, and are often implicated in cancer and immune signaling.
-
B.
epidermal growth factor receptor family
The epidermal growth factor receptor family is a group of closely related receptor tyrosine kinases (including EGFR/HER1, HER2, HER3, and HER4) that regulate cell growth, survival, and differentiation and are key targets in cancer biology and therapy.
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C.
Cdc25 homolog Mih1
Cdc25 homolog Mih1 is a yeast phosphatase that activates the cyclin-dependent kinase Cdc28 to promote entry into mitosis by removing inhibitory phosphorylations.
-
D.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
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E.
Janus kinase 1
Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Tec family kinases Target entity description: Tec family kinases are a group of non-receptor tyrosine kinases involved in signaling pathways that regulate lymphocyte development, activation, and function.
-
A.
Src family kinases
Src family kinases are a group of non-receptor tyrosine kinases that regulate key cellular processes such as proliferation, differentiation, survival, and migration, and are often implicated in cancer and immune signaling.
-
B.
epidermal growth factor receptor family
The epidermal growth factor receptor family is a group of closely related receptor tyrosine kinases (including EGFR/HER1, HER2, HER3, and HER4) that regulate cell growth, survival, and differentiation and are key targets in cancer biology and therapy.
-
C.
Cdc25 homolog Mih1
Cdc25 homolog Mih1 is a yeast phosphatase that activates the cyclin-dependent kinase Cdc28 to promote entry into mitosis by removing inhibitory phosphorylations.
-
D.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
E.
Janus kinase 1
Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.