hasClinicalSignificance
P47123
predicate
Indicates that something (such as a finding, variant, or condition) has a meaningful impact or relevance in a clinical or medical context.
All labels observed (8)
| Label | Occurrences |
|---|---|
| clinicalSignificance | 59 |
| hasClinicalRelevance | 21 |
| medicalRelevance | 21 |
| associatedWithClinicalFeature | 9 |
| hasClinicalSignificance canonical | 3 |
| hasClinicalUse | 2 |
| consideredClinicalEffectOnAlzheimersDisease | 1 |
| isMedicallyImportant | 1 |
Description generation (PDg)
The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.
Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning. # Instructions Focus on describing the relationship, not the entities themselves. # Response Format Begin the description with \' Indicates...\'
Input
Predicate: hasClinicalSignificance
Generated description
Indicates that something (such as a finding, variant, or condition) has a meaningful impact or relevance in a clinical or medical context.
Sample triples (117)
| Subject | Object |
|---|---|
| Virchow's triad | guides prevention of venous thromboembolism ⓘ |
| Virchow's triad | guides evaluation of thrombotic risk factors ⓘ |
| Claviceps purpurea | source of precursors for pharmaceutical drugs via predicate surface "medicalRelevance" ⓘ |
| Claviceps purpurea | source of compounds used in obstetrics via predicate surface "medicalRelevance" ⓘ |
| Claviceps purpurea | source of compounds used in migraine treatment via predicate surface "medicalRelevance" ⓘ |
| C9orf72 | behavioral variant frontotemporal dementia via predicate surface "associatedWithClinicalFeature" ⓘ |
| C9orf72 | bulbar-onset ALS via predicate surface "associatedWithClinicalFeature" ⓘ |
| C9orf72 | psychiatric symptoms via predicate surface "associatedWithClinicalFeature" ⓘ |
| ABO blood group system | hemolytic transfusion reactions via predicate surface "clinicalSignificance" ⓘ |
| ABO blood group system | hemolytic disease of the fetus and newborn (less common than Rh) via predicate surface "clinicalSignificance" ⓘ |
| ABO blood group system | organ transplant rejection risk via predicate surface "clinicalSignificance" ⓘ |
| thalamus | lesions can cause sensory loss via predicate surface "clinicalSignificance" ⓘ |
| thalamus | lesions can cause motor deficits via predicate surface "clinicalSignificance" ⓘ |
| thalamus | lesions can cause thalamic pain syndrome via predicate surface "clinicalSignificance" ⓘ |
| thalamus | lesions can impair consciousness via predicate surface "clinicalSignificance" ⓘ |
| thalamus | involved in some sleep disorders via predicate surface "clinicalSignificance" ⓘ |
| thalamus | involved in some attention disorders via predicate surface "clinicalSignificance" ⓘ |
| middle cerebral artery | most common site of ischemic stroke via predicate surface "clinicalSignificance" ⓘ |
| Bacillales | includes human pathogens via predicate surface "medicalRelevance" ⓘ |
| Bacillales | includes foodborne pathogens via predicate surface "medicalRelevance" ⓘ |
| Troisier's sign | marker of metastatic disease via predicate surface "hasClinicalRelevance" ⓘ |
| Troisier's sign | poor prognostic sign via predicate surface "hasClinicalRelevance" ⓘ |
| Agelaia | stings can cause severe allergic reactions in humans via predicate surface "medicalRelevance" ⓘ |
| Acanthocephala | zoonotic potential in humans via predicate surface "medicalRelevance" ⓘ |
| Ascarididae | important cause of human helminth infections via predicate surface "medicalRelevance" ⓘ |
| Secernentea | true via predicate surface "isMedicallyImportant" ⓘ |
| Oxyuridae | human intestinal parasite via predicate surface "medicalRelevance" ⓘ |
| Chironex fleckeri | can cause human fatalities via predicate surface "medicalRelevance" ⓘ |
| Chironex fleckeri | causes severe stings via predicate surface "medicalRelevance" ⓘ |
| Thoracic cavity | site of pleural effusion via predicate surface "clinicalSignificance" ⓘ |
| Thoracic cavity | site of pneumothorax via predicate surface "clinicalSignificance" ⓘ |
| Thoracic cavity | site of hemothorax via predicate surface "clinicalSignificance" ⓘ |
| Atrial septum | site for interatrial shunts via predicate surface "clinicalSignificance" ⓘ |
| Atrial septum | important in structural heart interventions via predicate surface "clinicalSignificance" ⓘ |
| Pulmonary artery | site of pulmonary embolism lodging via predicate surface "clinicalSignificance" ⓘ |
| Pulmonary artery | involved in pulmonary hypertension via predicate surface "clinicalSignificance" ⓘ |
| Pulmonary artery | can be affected by congenital heart disease via predicate surface "clinicalSignificance" ⓘ |
| Pulmonary veins | Site of origin of many atrial fibrillation triggers via predicate surface "clinicalSignificance" ⓘ |
| Superior vena cava | site of superior vena cava syndrome via predicate surface "clinicalSignificance" ⓘ |
| Superior vena cava | common site for central venous catheter placement via predicate surface "clinicalSignificance" ⓘ |
| Superior vena cava | may be compressed by mediastinal tumors via predicate surface "clinicalSignificance" ⓘ |
| Superior vena cava | may be obstructed by thrombosis via predicate surface "clinicalSignificance" ⓘ |
| Mitral valve | site of mitral regurgitation via predicate surface "clinicalSignificance" ⓘ |
| Mitral valve | site of mitral stenosis via predicate surface "clinicalSignificance" ⓘ |
| Mitral valve | site of mitral valve prolapse via predicate surface "clinicalSignificance" ⓘ |
| Mitral valve | can be affected by infective endocarditis via predicate surface "clinicalSignificance" ⓘ |
| Mitral valve | can be affected by rheumatic heart disease via predicate surface "clinicalSignificance" ⓘ |
| Inferior vena cava | can be affected by deep vein thrombosis extension via predicate surface "clinicalSignificance" ⓘ |
| Inferior vena cava | site of inferior vena cava filter placement via predicate surface "clinicalSignificance" ⓘ |
| Inferior vena cava | may be compressed in late pregnancy via predicate surface "clinicalSignificance" ⓘ |