downregulatedBy
P149277
predicate
Indicates that the level, activity, or expression of one entity is decreased as a result of the influence or action of another entity.
All labels observed (3)
| Label | Occurrences |
|---|---|
| downregulatedBy canonical | 5 |
| negativelyRegulatedBy | 3 |
| canDecreaseSynthesisOf | 2 |
Description generation (PDg)
The one-sentence description above was generated by prompting gpt-5.1 with the predicate name and this instruction.
Instruction
Given a predicate that represents a relationship or action between entities, generate a one-sentence description explaining its meaning. # Instructions Focus on describing the relationship, not the entities themselves. # Response Format Begin the description with \' Indicates...\'
Input
Predicate: downregulatedBy
Generated description
Indicates that the level, activity, or expression of one entity is decreased as a result of the influence or action of another entity.
Sample triples (10)
| Subject | Object |
|---|---|
| IL-17A | IL-27 ⓘ |
| IL-17A | IFN-γ ⓘ |
| IL-17A | IL-4 ⓘ |
| tumor necrosis factor alpha | glucocorticoid ⓘ |
| tumor necrosis factor alpha | IL-10 ⓘ |
| ketoconazole | cortisol via predicate surface "canDecreaseSynthesisOf" ⓘ |
| ketoconazole | testosterone via predicate surface "canDecreaseSynthesisOf" ⓘ |
| MAPK signaling pathway | MAPK phosphatases via predicate surface "negativelyRegulatedBy" ⓘ |
| MAPK signaling pathway | protein phosphatase 2A via predicate surface "negativelyRegulatedBy" ⓘ |
| MAPK signaling pathway | Sprouty proteins via predicate surface "negativelyRegulatedBy" ⓘ |