Docefrez
E902897
Docefrez is a branded formulation of the chemotherapy drug docetaxel used to treat various cancers, including breast, lung, and prostate cancer.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Docefrez canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T11074696 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Docefrez Context triple: [Docetaxel, tradeName, Docefrez]
-
A.
Fenodyree
Fenodyree is a mythical, goblin-like creature from Alan Garner’s fantasy novel "The Weirdstone of Brisingamen," known for aiding the protagonists with its otherworldly powers and knowledge of the hidden realms.
-
B.
Bunefer
Bunefer was an ancient Egyptian queen of the late Fourth Dynasty, likely known from her tomb at Giza and associated with the royal family of that period.
-
C.
Toclafane
The Toclafane are a race of deadly, cybernetic spheres revealed to be the future remnants of humanity in the Doctor Who universe, serving as instruments of mass destruction under the Master.
-
D.
Doxato
Doxato is a town in northern Greece located within the Drama regional unit, known for its agricultural surroundings and historical significance.
-
E.
Daypro
Daypro is a prescription nonsteroidal anti-inflammatory drug (NSAID) containing oxaprozin, used to relieve pain and inflammation in conditions such as osteoarthritis and rheumatoid arthritis.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Docefrez Target entity description: Docefrez is a branded formulation of the chemotherapy drug docetaxel used to treat various cancers, including breast, lung, and prostate cancer.
-
A.
Fenodyree
Fenodyree is a mythical, goblin-like creature from Alan Garner’s fantasy novel "The Weirdstone of Brisingamen," known for aiding the protagonists with its otherworldly powers and knowledge of the hidden realms.
-
B.
Bunefer
Bunefer was an ancient Egyptian queen of the late Fourth Dynasty, likely known from her tomb at Giza and associated with the royal family of that period.
-
C.
Toclafane
The Toclafane are a race of deadly, cybernetic spheres revealed to be the future remnants of humanity in the Doctor Who universe, serving as instruments of mass destruction under the Master.
-
D.
Doxato
Doxato is a town in northern Greece located within the Drama regional unit, known for its agricultural surroundings and historical significance.
-
E.
Daypro
Daypro is a prescription nonsteroidal anti-inflammatory drug (NSAID) containing oxaprozin, used to relieve pain and inflammation in conditions such as osteoarthritis and rheumatoid arthritis.
- F. None of above. chosen
Statements (39)
| Predicate | Object |
|---|---|
| instanceOf |
chemotherapy drug
ⓘ
pharmaceutical brand ⓘ |
| administeredBy | healthcare professional ⓘ |
| affects | microtubule depolymerization ⓘ |
| belongsToClass | taxane chemotherapy ⓘ |
| causes | apoptosis in cancer cells ⓘ |
| commonAdverseEffect |
alopecia
ⓘ
anemia ⓘ fatigue ⓘ nausea ⓘ neutropenia ⓘ peripheral neuropathy ⓘ |
| contains | docetaxel anhydrous ⓘ |
| contraindicatedIn | severe hepatic impairment ⓘ |
| drugClass | antineoplastic agent ⓘ |
| formulationType | injectable concentrate ⓘ |
| hasActiveIngredient | docetaxel ⓘ |
| indicatedFor |
hormone-refractory metastatic prostate cancer
ⓘ
locally advanced breast cancer ⓘ metastatic breast cancer ⓘ metastatic non-small cell lung cancer ⓘ |
| induces | cell cycle arrest at G2/M phase ⓘ |
| mayCause | hypersensitivity reactions ⓘ |
| mechanismOfAction |
microtubule stabilizer
ⓘ
mitotic inhibitor ⓘ |
| oftenGivenWith | corticosteroid premedication ⓘ |
| originatesFrom | semi-synthetic derivative of paclitaxel-related compounds ⓘ |
| pregnancyCategory | teratogenic risk ⓘ |
| regulatoryStatus | prescription-only medicine ⓘ |
| requires |
dilution before infusion
ⓘ
prescription ⓘ |
| requiresMonitoring | blood cell counts ⓘ |
| routeOfAdministration | intravenous infusion ⓘ |
| storageCondition | controlled room temperature ⓘ |
| targets | rapidly dividing cells ⓘ |
| usedFor |
breast cancer
ⓘ
cancer treatment ⓘ non-small cell lung cancer ⓘ prostate cancer ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Docefrez Description of subject: Docefrez is a branded formulation of the chemotherapy drug docetaxel used to treat various cancers, including breast, lung, and prostate cancer.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.