bacteriophage lambda

E629012

Bacteriophage lambda is a temperate virus that infects Escherichia coli and serves as a classic model system for studying gene regulation, lysogeny, and molecular genetics.

All labels observed (2)

How this entity was disambiguated

Statements (61)

Predicate Object
instanceOf Siphoviridae ⓘ
double-stranded DNA virus ⓘ
temperate bacteriophage ⓘ
virus ⓘ
belongsToFamily Siphoviridae ⓘ
belongsToOrder Caudovirales ⓘ
cosSiteLength 12 nucleotides ⓘ
decisionProcess lysis-lysogeny switch ⓘ
discoveredBy Esther Lederberg ⓘ
discoveryYear 1950 ⓘ
encodes CI repressor ⓘ
CII protein ⓘ
CIII protein ⓘ
Cro protein ⓘ
Gam protein ⓘ
Int integrase ⓘ
N antiterminator protein ⓘ
Q antiterminator protein ⓘ
Red recombination proteins ⓘ
Xis excisionase ⓘ
head and tail structural proteins ⓘ
genomeSize approximately 48.5 kilobase pairs ⓘ
genomeType linear double-stranded DNA ⓘ
hasCohesiveEnds cos sites ⓘ
hasGCContent approximately 50 percent ⓘ
hasLifeCycle lysogenic cycle ⓘ
lytic cycle ⓘ
hasMorphology icosahedral head with long noncontractile tail ⓘ
hasOperator OL operator region ⓘ
OR operator region ⓘ
hasPackagingLimit approximately 52 kilobase pairs ⓘ
hasRegulatoryRegion PL promoter ⓘ
PR promoter ⓘ
PRM promoter ⓘ
host Escherichia coli K-12 ⓘ
linked to: Escherichia coli
inducedBy DNA damage ⓘ
inductionMechanism SOS response mediated CI cleavage ⓘ
infects Escherichia coli ⓘ
integratesInto E. coli chromosome ⓘ
integrationSite attB site in E. coli ⓘ
between gal and bio operons in E. coli ⓘ
isTemperate true ⓘ
keyRegulator CI repressor ⓘ
Cro protein ⓘ
keyRegulator CII protein ⓘ
N protein ⓘ
Q protein ⓘ
prophageForm integrated into host chromosome ⓘ
repressorMaintains prophage state ⓘ
requiresForIntegration host IHF protein ⓘ
requiresForReplication host DNA replication machinery ⓘ
tailType long noncontractile tail ⓘ
taxonRank species ⓘ
usedAs cloning vector ⓘ
phage display vector ⓘ
usedAsModelFor developmental decision-making in phages ⓘ
gene regulation ⓘ
lysogeny ⓘ
molecular genetics ⓘ
site-specific recombination ⓘ
transcriptional regulation ⓘ

How these facts were elicited

Referenced by (3)

Full triples — surface form annotated when it differs from this entity's canonical label.

Gunther Stent → researchSubject → bacteriophage lambda ⓘ
A Genetic Switch: Phage Lambda and Higher Organisms → usesModelOrganism → Escherichia coli bacteriophage lambda ⓘ
linked to: bacteriophage lambda