Aristada

E597293

Aristada is a long-acting injectable antipsychotic medication (aripiprazole lauroxil) used primarily to treat schizophrenia in adults.

All labels observed (2)

Label Occurrences
Aristada canonical 2
Aristada Initio 2

How this entity was disambiguated

Statements (49)

Predicate Object
instanceOf atypical antipsychotic ⓘ
brand name drug ⓘ
long-acting injectable antipsychotic medication ⓘ
approvalYearUS 2015 ⓘ
approvedBy U.S. Food and Drug Administration ⓘ
ATCCode N05AX12 (aripiprazole) ⓘ
availableStrength 1064 mg ⓘ
441 mg ⓘ
662 mg ⓘ
882 mg ⓘ
commonAdverseEffect akathisia ⓘ
anxiety ⓘ
injection site pain ⓘ
insomnia ⓘ
weight gain ⓘ
countryApprovedIn United States ⓘ
dosingInterval every 4 weeks ⓘ
every 6 weeks ⓘ
every 8 weeks ⓘ
formulation extended-release injectable suspension ⓘ
hasActiveIngredient aripiprazole lauroxil ⓘ
hasBoxedWarning increased mortality in elderly patients with dementia-related psychosis ⓘ
hasLoadingDoseOption true ⓘ
indicatedFor schizophrenia in adults ⓘ
injectionSite deltoid muscle (for some doses) ⓘ
gluteal muscle ⓘ
isLongActing true ⓘ
isProdrugOf aripiprazole ⓘ
legalStatusUS prescription only ⓘ
loadingRegimenBrand Aristada Initio ⓘ
linked to: Aristada
marketingAuthorizationHolder Alkermes plc ⓘ
linked to: Alkermes
metabolism CYP2D6 ⓘ
CYP3A4 ⓘ
notApprovedFor treatment of dementia-related psychosis ⓘ
oralOverlapDrug oral aripiprazole ⓘ
oralOverlapDuration 21 days (for most initiation regimens) ⓘ
pharmacologicClass dopamine D2 receptor partial agonist ⓘ
serotonin 5-HT1A receptor partial agonist ⓘ
serotonin 5-HT2A receptor antagonist ⓘ
pregnancyCategoryUS not assigned (use only if benefit justifies risk) ⓘ
requiresOralOverlap true ⓘ
routeOfAdministration intramuscular injection ⓘ
seriousAdverseEffect leukopenia ⓘ
neuroleptic malignant syndrome ⓘ
orthostatic hypotension ⓘ
seizures ⓘ
tardive dyskinesia ⓘ
targetPopulation adults with schizophrenia ⓘ
therapeuticArea psychiatry ⓘ

How these facts were elicited

Referenced by (4)

Full triples — surface form annotated when it differs from this entity's canonical label.

Alkermes → product → Aristada ⓘ
Alkermes → product → Aristada Initio ⓘ
linked to: Aristada
Alkermes plc → notableProduct → Aristada ⓘ
subject linked to: ALKS
Aristada → loadingRegimenBrand → Aristada Initio ⓘ
linked to: Aristada