Aubagio
E561778
Aubagio is a prescription oral medication (teriflunomide) used to treat relapsing forms of multiple sclerosis in adults.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Aubagio canonical | 2 |
How this entity was disambiguated
This entity first appeared as the object of triple T6006203 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Aubagio Context triple: [Sanofi, hasBrand, Aubagio]
-
A.
Olesko
Olesko is a historic town in western Ukraine best known for its medieval castle, which served as the birthplace of Polish King John III Sobieski.
-
B.
Tartegnin
Tartegnin is a small wine-producing municipality in the canton of Vaud in western Switzerland, situated above Lake Geneva in the La Côte region.
-
C.
Arbogne
Arbogne is a small river in western Switzerland that serves as a tributary of the Broye.
-
D.
Novaro
Novaro is an Italian surname most notably borne by Michele Novaro, the composer of Italy’s national anthem.
-
E.
Asolo
Asolo is a picturesque historic town in Italy’s Veneto region, renowned for its medieval architecture, hillside setting, and association with artists and writers.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Aubagio Target entity description: Aubagio is a prescription oral medication (teriflunomide) used to treat relapsing forms of multiple sclerosis in adults.
-
A.
Olesko
Olesko is a historic town in western Ukraine best known for its medieval castle, which served as the birthplace of Polish King John III Sobieski.
-
B.
Tartegnin
Tartegnin is a small wine-producing municipality in the canton of Vaud in western Switzerland, situated above Lake Geneva in the La Côte region.
-
C.
Arbogne
Arbogne is a small river in western Switzerland that serves as a tributary of the Broye.
-
D.
Novaro
Novaro is an Italian surname most notably borne by Michele Novaro, the composer of Italy’s national anthem.
-
E.
Asolo
Asolo is a picturesque historic town in Italy’s Veneto region, renowned for its medieval architecture, hillside setting, and association with artists and writers.
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
brand name drug
ⓘ
disease-modifying therapy for multiple sclerosis ⓘ pharmaceutical drug ⓘ |
| hasActiveIngredient | teriflunomide ⓘ |
| hasATCCode | L04AA31 ⓘ |
| hasBlackBoxWarning |
embryo-fetal toxicity
ⓘ
hepatotoxicity ⓘ |
| hasBoxedWarningRegion |
United States
ⓘ
linked to:
United States of America
|
| hasDosageForm | oral tablet ⓘ |
| hasEffect |
reduces relapse rate in relapsing multiple sclerosis
ⓘ
slows accumulation of physical disability in multiple sclerosis ⓘ |
| hasEliminationProcedure |
activated charcoal washout
ⓘ
cholestyramine washout ⓘ |
| hasGenericName | teriflunomide ⓘ |
| hasIndicationPopulation | adults ⓘ |
| hasLongHalfLife | true ⓘ |
| hasPharmacologicClass |
immunomodulator
ⓘ
pyrimidine synthesis inhibitor ⓘ |
| hasPregnancyCategory | contraindicated ⓘ |
| hasRegulatoryAgencyApproval |
European Medicines Agency
ⓘ
U.S. Food and Drug Administration ⓘ
linked to:
Food and Drug Administration
|
| hasRisk |
infections due to immunosuppression
ⓘ
serious liver injury ⓘ serious skin reactions ⓘ |
| hasRouteOfAdministration | oral ⓘ |
| hasRouteOfElimination | hepatic ⓘ |
| hasTeratogenicRisk | true ⓘ |
| isAdministeredOnceDaily | true ⓘ |
| isContraindicatedIn |
pregnancy
ⓘ
severe hepatic impairment ⓘ |
| isMarketedBy | Sanofi ⓘ |
| isMetabolizedIn | liver ⓘ |
| isPrescriptionDrug | true ⓘ |
| isTakenWithFood | may be taken with or without food ⓘ |
| isUsedFor |
active secondary progressive multiple sclerosis
ⓘ
clinically isolated syndrome (CIS) ⓘ relapsing forms of multiple sclerosis ⓘ relapsing-remitting multiple sclerosis ⓘ |
| mayCause |
alopecia (hair thinning)
ⓘ
diarrhea ⓘ elevated liver enzymes ⓘ hypertension ⓘ nausea ⓘ peripheral neuropathy ⓘ |
| mechanismOfAction |
inhibits dihydroorotate dehydrogenase (DHODH)
ⓘ
reduces proliferation of activated T and B lymphocytes ⓘ |
| requiresMonitoring |
blood pressure
ⓘ
liver function tests ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Aubagio Description of subject: Aubagio is a prescription oral medication (teriflunomide) used to treat relapsing forms of multiple sclerosis in adults.
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.