Singulair
E468961
Singulair is a prescription leukotriene receptor antagonist (montelukast) commonly used to prevent and manage asthma and allergy symptoms.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Singulair canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T4784893 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Singulair Context triple: [Merck & Co., notableDrug, Singulair]
-
A.
Opekta
Opekta was a German-Dutch company that produced and sold pectin-based gelling agents for making jam, notably managed in its Amsterdam branch by Anne Frank’s father, Otto Frank.
-
B.
Optax
Optax is a gradient processing and optimization library for JAX, providing a flexible collection of composable optimizers and transformations for training machine learning models.
-
C.
Novafora
Novafora was a semiconductor company known for acquiring Transmeta to expand its presence in low-power microprocessor and video processing technologies.
-
D.
Plaxtol
Plaxtol is a small rural village and civil parish in Kent, England, known for its historic buildings and surrounding countryside.
-
E.
Versonnex
Versonnex is a small commune in the Ain department of eastern France, located near the Swiss border in the Pays de Gex region.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Singulair Target entity description: Singulair is a prescription leukotriene receptor antagonist (montelukast) commonly used to prevent and manage asthma and allergy symptoms.
-
A.
Opekta
Opekta was a German-Dutch company that produced and sold pectin-based gelling agents for making jam, notably managed in its Amsterdam branch by Anne Frank’s father, Otto Frank.
-
B.
Optax
Optax is a gradient processing and optimization library for JAX, providing a flexible collection of composable optimizers and transformations for training machine learning models.
-
C.
Novafora
Novafora was a semiconductor company known for acquiring Transmeta to expand its presence in low-power microprocessor and video processing technologies.
-
D.
Plaxtol
Plaxtol is a small rural village and civil parish in Kent, England, known for its historic buildings and surrounding countryside.
-
E.
Versonnex
Versonnex is a small commune in the Ain department of eastern France, located near the Swiss border in the Pays de Gex region.
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
brand name drug
ⓘ
pharmaceutical drug ⓘ |
| actsOn | cysteinyl leukotriene receptor CysLT1 ⓘ |
| boxedWarning | risk of serious neuropsychiatric events ⓘ |
| brandNameOf | montelukast ⓘ |
| commonSideEffect |
abdominal pain
ⓘ
cough ⓘ headache ⓘ upper respiratory infection ⓘ |
| contraindication | hypersensitivity to montelukast ⓘ |
| dosageForm |
chewable tablet
ⓘ
film-coated tablet ⓘ oral granules ⓘ |
| dosingFrequency | once daily ⓘ |
| drugClass |
anti-asthmatic agent
ⓘ
leukotriene receptor antagonist ⓘ respiratory system drug ⓘ |
| eliminationRoute | biliary excretion ⓘ |
| firstApprovalRegion |
United States
ⓘ
linked to:
United States of America
|
| hasActiveIngredient | montelukast sodium ⓘ |
| hasATCCode | R03DC03 ⓘ |
| hasBlackBoxWarningRegion |
United States
ⓘ
linked to:
United States of America
|
| hasGenericName | montelukast ⓘ |
| indication |
asthma prophylaxis
ⓘ
chronic asthma management ⓘ exercise-induced bronchoconstriction prevention ⓘ perennial allergic rhinitis ⓘ seasonal allergic rhinitis ⓘ |
| lactationUse | caution advised ⓘ |
| marketingAuthorizationHolder | Merck & Co. ⓘ |
| mechanismOfAction |
inhibits leukotriene-mediated bronchoconstriction
ⓘ
reduces airway inflammation ⓘ selective leukotriene receptor antagonist ⓘ |
| metabolism | hepatic ⓘ |
| metabolizingEnzyme |
CYP2C9
ⓘ
CYP3A4 ⓘ |
| notForUse | acute asthma attacks relief ⓘ |
| onsetOfAction | within hours ⓘ |
| pregnancyCategory | data suggest low risk but use if clearly needed ⓘ |
| regulatoryStatus | prescription only ⓘ |
| routeOfAdministration | oral ⓘ |
| seriousSideEffect |
agitation
ⓘ
depression ⓘ neuropsychiatric events ⓘ suicidal thoughts ⓘ |
| targetPopulation |
adults with asthma
ⓘ
children with asthma ⓘ patients with allergic rhinitis ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Singulair Description of subject: Singulair is a prescription leukotriene receptor antagonist (montelukast) commonly used to prevent and manage asthma and allergy symptoms.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.