pPCP1

E357723

pPCP1 is a virulence-associated plasmid of the plague bacterium Yersinia pestis that encodes key factors such as the plasminogen activator protease.

All labels observed (3)

How this entity was disambiguated

Statements (51)

Predicate Object
instanceOf plasmid
virulence plasmid
associatedWithDisease plague
carriedBy Yersinia pestis CO92
linked to: Yersinia pestis

Yersinia pestis KIM
linked to: Yersinia pestis

Yersinia pestis biovar Antiqua strains
Yersinia pestis biovar Medievalis strains
linked to: Yersinia pestis

Yersinia pestis biovar Orientalis strains
linked to: Yersinia pestis
contributesTo bacterial spread from initial infection site
degradation of host complement components
fibrinolysis in host
inactivation of plasmin inhibitor alpha-2-antiplasmin
discoveredInContextOf plague pathogenesis studies
encodes Pla
outer membrane protease Pla
plasminogen activator protease
foundInSpecies Yersinia pestis
geneticElementOf Yersinia pestis genome complement
hasApproximateSize 9.5 kb
hasGene pPCP1.02 (putative transposase)
linked to: pPCP1

pPCP1.03 (hypothetical protein)
pPCP1.04 (hypothetical protein)
pPCP1.05 (hypothetical protein)
pPCP1.06 (hypothetical protein)
pPCP1.07 (hypothetical protein)
pPCP1.08 (hypothetical protein)
linked to: pPCP1

pPCP1.09 (hypothetical protein)
pPCP1.10 (hypothetical protein)
pPCP1.11 (hypothetical protein)
pPCP1.12 (hypothetical protein)
pPCP1.13 (hypothetical protein)
pPCP1.14 (hypothetical protein)
pPCP1.15 (hypothetical protein)
pPCP1.16 (hypothetical protein)
pPCP1.17 (hypothetical protein)
pPCP1.18 (hypothetical protein)
pPCP1.19 (hypothetical protein)
pPCP1.20 (hypothetical protein)
pla
pst
hasMolecularFunctionViaPla plasminogen activator activity
serine protease activity
hasVirulenceFactor Pla protease
plasminogen activator
isCircular true
requiredFor full virulence of Yersinia pestis in mammalian hosts
roleIn dissemination of Yersinia pestis in mammalian host
flea-borne transmission of Yersinia pestis
invasion of host tissues
virulence of Yersinia pestis
taxonOfOrigin Enterobacteriaceae
linked to: Enterobacterales

How these facts were elicited

Referenced by (3)

Full triples — surface form annotated when it differs from this entity's canonical label.

pPCP1 hasGene pPCP1.02 (putative transposase)
linked to: pPCP1
pPCP1 hasGene pPCP1.08 (hypothetical protein)
linked to: pPCP1