pMT1

E357722

pMT1 is a virulence plasmid of Yersinia pestis that carries key genes, including the murine toxin gene, essential for the bacterium’s pathogenicity and flea-borne transmission.

All labels observed (1)

Label Occurrences
pMT1 canonical 1

How this entity was disambiguated

Statements (39)

Predicate Object
instanceOf plasmid ⓘ
virulence plasmid ⓘ
associatedWithDisease plague ⓘ
associatedWithPathotype highly virulent Yersinia pestis strains ⓘ
biosafetyRelevance biodefense and high-consequence pathogen research ⓘ
carriersGene caf1 ⓘ
fraction 1 capsule antigen gene ⓘ
murine toxin gene ⓘ
pH 6 antigen gene ⓘ
psaA ⓘ
ymt ⓘ
carriersLocus fra locus ⓘ
ymt locus ⓘ
contributesTo environmental persistence in flea gut ⓘ
resistance to phagocytosis via capsule formation ⓘ
discoveredInContextOf plague virulence studies ⓘ
DNAType circular double-stranded DNA ⓘ
encodes F1 capsule antigen ⓘ
Yersinia murine toxin ⓘ
pH 6 antigen ⓘ
foundInTaxon Yersinia pestis ⓘ
geneticElementOf Yersinia pestis CO92 ⓘ
linked to: Yersinia pestis

Yersinia pestis KIM ⓘ
linked to: Yersinia pestis
hasAlternativeName F1 plasmid ⓘ
pFra ⓘ
hostRange narrow, mainly Yersinia pestis ⓘ
importanceInResearch model for studying flea-borne transmission mechanisms ⓘ
target for attenuation in vaccine strain development ⓘ
involvedIn oral toxicity to rodents ⓘ
survival of Yersinia pestis in flea vector ⓘ
isMobileGeneticElement true ⓘ
isNonChromosomal true ⓘ
location cytoplasm of Yersinia pestis ⓘ
molecularFunctionContext virulence factor expression platform ⓘ
requiredFor blockage-dependent flea transmission ⓘ
efficient colonization of flea midgut ⓘ
roleIn flea-borne transmission of Yersinia pestis ⓘ
pathogenicity of Yersinia pestis ⓘ
taxonSpecificity primarily Yersinia pestis ⓘ

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.