Avram Hershko
E307112
Avram Hershko is an Israeli biochemist and Nobel laureate renowned for his pioneering work on the ubiquitin-mediated protein degradation pathway.
All labels observed (2)
| Label | Occurrences |
|---|---|
| Avram Hershko canonical | 11 |
| Hershko | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T2860666 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Avram Hershko Context triple: [Lasker Basic Award, notableLaureate, Avram Hershko]
-
A.
Aaron Ciechanover
Aaron Ciechanover is an Israeli biochemist and Nobel laureate renowned for his pioneering work on the ubiquitin-mediated protein degradation pathway.
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B.
Yoshinori Ohsumi
Yoshinori Ohsumi is a Japanese cell biologist and Nobel laureate renowned for his pioneering discoveries on the mechanisms of autophagy.
-
C.
Herbert A. Hauptman
Herbert A. Hauptman was an American mathematician and crystallographer renowned for developing direct methods for determining crystal structures, work that earned him the Nobel Prize in Chemistry.
-
D.
Severo Ochoa
Severo Ochoa was a Spanish-American biochemist and molecular biologist who won the 1959 Nobel Prize in Physiology or Medicine for his work on the synthesis of RNA.
-
E.
Aziz Sancar
Aziz Sancar is a Turkish-American biochemist and molecular biologist who won the 2015 Nobel Prize in Chemistry for his pioneering work on DNA repair mechanisms.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Avram Hershko Target entity description: Avram Hershko is an Israeli biochemist and Nobel laureate renowned for his pioneering work on the ubiquitin-mediated protein degradation pathway.
-
A.
Aaron Ciechanover
Aaron Ciechanover is an Israeli biochemist and Nobel laureate renowned for his pioneering work on the ubiquitin-mediated protein degradation pathway.
-
B.
Yoshinori Ohsumi
Yoshinori Ohsumi is a Japanese cell biologist and Nobel laureate renowned for his pioneering discoveries on the mechanisms of autophagy.
-
C.
Herbert A. Hauptman
Herbert A. Hauptman was an American mathematician and crystallographer renowned for developing direct methods for determining crystal structures, work that earned him the Nobel Prize in Chemistry.
-
D.
Severo Ochoa
Severo Ochoa was a Spanish-American biochemist and molecular biologist who won the 1959 Nobel Prize in Physiology or Medicine for his work on the synthesis of RNA.
-
E.
Aziz Sancar
Aziz Sancar is a Turkish-American biochemist and molecular biologist who won the 2015 Nobel Prize in Chemistry for his pioneering work on DNA repair mechanisms.
- F. None of above. chosen
Statements (43)
| Predicate | Object |
|---|---|
| instanceOf |
Israeli scientist
ⓘ
Nobel laureate ⓘ biochemist ⓘ human ⓘ |
| almaMater | Hebrew University of Jerusalem ⓘ |
| awardReceived |
Albert Lasker Award for Basic Medical Research
ⓘ
Israel Prize in biochemistry ⓘ
linked to:
Israel Prize in exact sciences
Nobel Prize in Chemistry ⓘ |
| citizenship | Israel ⓘ |
| countryOfBirth | Hungary ⓘ |
| dateOfBirth | 1937-12-31 ⓘ |
| degree |
MD
ⓘ
PhD ⓘ |
| developedConcept | ATP-dependent protein degradation via ubiquitin ⓘ |
| discovered | role of ubiquitin in targeting proteins for degradation ⓘ |
| employer | Technion – Israel Institute of Technology ⓘ |
| era |
20th-century biochemistry
ⓘ
21st-century biochemistry ⓘ |
| ethnicGroup | Jewish ⓘ |
| familyName |
Hershko
ⓘ
linked to:
Avram Hershko
|
| fieldOfWork |
biochemistry
ⓘ
molecular biology ⓘ |
| gender | male ⓘ |
| givenName | Avram ⓘ |
| influenced | modern cancer research on proteasome inhibitors ⓘ |
| knownFor |
discovery of the ubiquitin-proteasome system
ⓘ
ubiquitin-mediated protein degradation ⓘ |
| memberOf | Israel Academy of Sciences and Humanities ⓘ |
| migration | emigrated from Hungary to Israel ⓘ |
| name | Avram Hershko ⓘ |
| nationality | Israeli ⓘ |
| NobelPrizeCategory | Chemistry ⓘ |
| NobelPrizeYear | 2004 ⓘ |
| notableStudent | Aaron Ciechanover ⓘ |
| placeOfBirth | Karcsag ⓘ |
| positionHeld | professor of biochemistry ⓘ |
| reasonForAward | discovery of ubiquitin-mediated protein degradation ⓘ |
| religion | Judaism ⓘ |
| researchFocus |
cell cycle regulation
ⓘ
protein degradation ⓘ |
| sharedNobelPrizeWith |
Aaron Ciechanover
ⓘ
Irwin Rose ⓘ |
| workplace |
Rappaport Faculty of Medicine, Technion
ⓘ
linked to:
Rappaport Faculty of Medicine
|
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Avram Hershko Description of subject: Avram Hershko is an Israeli biochemist and Nobel laureate renowned for his pioneering work on the ubiquitin-mediated protein degradation pathway.
Referenced by (12)
Full triples — surface form annotated when it differs from this entity's canonical label.