David Sinclair (biologist)

E290015

author biologist podcast host university professor

David Sinclair is an Australian biologist and Harvard Medical School professor best known for his pioneering research on aging, sirtuins, and longevity therapeutics.

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All labels observed (4)

Label	Occurrences
David A. Sinclair	2
David Sinclair	2
David Andrew Sinclair	1
David Sinclair (biologist) canonical	1

How this entity was disambiguated

This entity first appeared as the object of triple T2705657 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.

NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07

Target entity: David Sinclair (biologist)
Context triple: [Sinclair, hasNotableBearer, David Sinclair (biologist)]

A. Douglas Ainslie
Douglas Ainslie is a mild-mannered, retired British man seeking a new start in India in the film "The Best Exotic Marigold Hotel," portrayed by Bill Nighy.
B. Spencer de Grey
Spencer de Grey is a prominent British architect and senior partner at Foster + Partners, known for his leadership in major international architectural projects.
C. Dr. Jim Bayliss
Dr. Jim Bayliss is a disillusioned physician and neighbor in Arthur Miller’s play "All My Sons," whose moral conflict and cynicism highlight the play’s themes of compromised ideals and social responsibility.
D. Sean B. Carroll
Sean B. Carroll is an evolutionary biologist, author, and science communicator known for his work in evolutionary developmental biology and for popularizing science through award-winning books and media.
E. Sydney Brenner
Sydney Brenner was a pioneering South African biologist and Nobel Prize laureate renowned for his foundational work in molecular biology and the use of C. elegans as a model organism.
F. None of above. chosen
G. Unsure - the case is ambiguous/there is not enough information to decide.

NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07

Target entity: David Sinclair (biologist)
Target entity description: David Sinclair is an Australian biologist and Harvard Medical School professor best known for his pioneering research on aging, sirtuins, and longevity therapeutics.

A. Douglas Ainslie
Douglas Ainslie is a mild-mannered, retired British man seeking a new start in India in the film "The Best Exotic Marigold Hotel," portrayed by Bill Nighy.
B. Spencer de Grey
Spencer de Grey is a prominent British architect and senior partner at Foster + Partners, known for his leadership in major international architectural projects.
C. Dr. Jim Bayliss
Dr. Jim Bayliss is a disillusioned physician and neighbor in Arthur Miller’s play "All My Sons," whose moral conflict and cynicism highlight the play’s themes of compromised ideals and social responsibility.
D. Sean B. Carroll
Sean B. Carroll is an evolutionary biologist, author, and science communicator known for his work in evolutionary developmental biology and for popularizing science through award-winning books and media.
E. Sydney Brenner
Sydney Brenner was a pioneering South African biologist and Nobel Prize laureate renowned for his foundational work in molecular biology and the use of C. elegans as a model organism.
F. None of above. chosen

Statements (57)

Predicate	Object
instanceOf	author ⓘ biologist ⓘ podcast host ⓘ university professor ⓘ
academicDegree	PhD in Molecular Genetics ⓘ
authorOf	Lifespan: Why We Age—and Why We Don’t Have To ⓘ
awardReceived	Australian Commonwealth Prize for Science and Innovation ⓘ Merck Prize ⓘ Nathan Shock Award ⓘ TIME 100 Most Influential People (2014) ⓘ linked to: Time 100 Most Influential People
birthName	David Andrew Sinclair ⓘ linked to: David Sinclair (biologist)
coFounded	Cohbar ⓘ EdenRoc Sciences ⓘ Genocea Biosciences ⓘ Life Biosciences ⓘ MetroBiotech ⓘ Ovascience ⓘ
countryOfCitizenship	Australia ⓘ
dateOfBirth	1969-06-26 ⓘ
doctoralAdvisor	Lindsay Wu ⓘ
educatedAt	University of New South Wales ⓘ
employer	Harvard Medical School ⓘ
familyName	Sinclair ⓘ
fieldOfWork	aging research ⓘ biology ⓘ epigenetics ⓘ genetics ⓘ gerontology ⓘ longevity therapeutics ⓘ
founded	Sirtris Pharmaceuticals ⓘ
givenName	David ⓘ
hasPodcast	Lifespan with Dr. David Sinclair ⓘ The Sinclair Lab Podcast ⓘ
hasResearchLab	Sinclair Lab at Harvard Medical School ⓘ
jobTitle	Professor of Genetics ⓘ
knownFor	NAD+ metabolism research ⓘ longevity interventions ⓘ research on aging ⓘ research on sirtuins ⓘ
languageOfWorkOrName	English ⓘ
name	David Sinclair ⓘ linked to: David Sinclair (biologist)
notableIdea	information theory of aging ⓘ view of aging as a treatable disease ⓘ
notableWork	demonstrating roles of sirtuins in aging ⓘ epigenetic information theory of aging ⓘ studies on resveratrol as a sirtuin activator ⓘ work on NAD+ boosters such as NMN and NR ⓘ
placeOfBirth	Sydney ⓘ
positionHeld	Co-Director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School ⓘ
researchInterest	DNA damage and repair ⓘ NAD+ precursors ⓘ caloric restriction mimetics ⓘ epigenetic reprogramming ⓘ resveratrol ⓘ sirtuin activators ⓘ
residence	Boston ⓘ
workplace	Harvard Medical School ⓘ

How these facts were elicited

Referenced by (6)

Full triples — surface form annotated when it differs from this entity's canonical label.

Sinclair → hasNotableBearer → David Sinclair (biologist) ⓘ

David Sinclair → name → David Sinclair ⓘ

subject linked to: David Sinclair (biologist)