Triple

T22690316
Position Surface form Disambiguated ID Type / Status
Subject CDK4 E561032 entity
Predicate inhibitedByDrug P149275 FINISHED
Object trilaciclib
Trilaciclib is an intravenous cyclin-dependent kinase 4/6 inhibitor used to protect bone marrow from chemotherapy-induced damage in patients with certain cancers.
 E1549322 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: trilaciclib | Statement: [CDK4, inhibitedByDrug, trilaciclib]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: trilaciclib
Context triple: [CDK4, inhibitedByDrug, trilaciclib]
  • A. paclitaxel
    Paclitaxel is a chemotherapy drug that stabilizes microtubules to inhibit cell division and is widely used to treat various cancers, including breast, ovarian, and lung cancers.
  • B. Ibrance
    Ibrance is a targeted oral cancer medication (palbociclib) used primarily to treat certain types of hormone receptor–positive, HER2-negative advanced or metastatic breast cancer.
  • C. Zaltrap
    Zaltrap is a cancer medication (brand name for aflibercept) used primarily in combination chemotherapy to treat metastatic colorectal cancer by inhibiting vascular endothelial growth factor (VEGF).
  • D. Abraxane
    Abraxane is a nanoparticle albumin-bound formulation of the chemotherapy drug paclitaxel used to treat various cancers, including breast, lung, and pancreatic cancer.
  • E. Alimta
    Alimta is a chemotherapy drug (pemetrexed) primarily used to treat malignant pleural mesothelioma and non-small cell lung cancer.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: trilaciclib
Triple: [CDK4, inhibitedByDrug, trilaciclib]
Generated description
Trilaciclib is an intravenous cyclin-dependent kinase 4/6 inhibitor used to protect bone marrow from chemotherapy-induced damage in patients with certain cancers.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: trilaciclib
Target entity description: Trilaciclib is an intravenous cyclin-dependent kinase 4/6 inhibitor used to protect bone marrow from chemotherapy-induced damage in patients with certain cancers.
  • A. paclitaxel
    Paclitaxel is a chemotherapy drug that stabilizes microtubules to inhibit cell division and is widely used to treat various cancers, including breast, ovarian, and lung cancers.
  • B. Ibrance
    Ibrance is a targeted oral cancer medication (palbociclib) used primarily to treat certain types of hormone receptor–positive, HER2-negative advanced or metastatic breast cancer.
  • C. Zaltrap
    Zaltrap is a cancer medication (brand name for aflibercept) used primarily in combination chemotherapy to treat metastatic colorectal cancer by inhibiting vascular endothelial growth factor (VEGF).
  • D. Abraxane
    Abraxane is a nanoparticle albumin-bound formulation of the chemotherapy drug paclitaxel used to treat various cancers, including breast, lung, and pancreatic cancer.
  • E. Alimta
    Alimta is a chemotherapy drug (pemetrexed) primarily used to treat malignant pleural mesothelioma and non-small cell lung cancer.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69e2454d71b48190a1f80af9f82b6fcf completed April 17, 2026, 2:35 p.m.
NER Named-entity recognition batch_69f1789a1fd08190bce5fa0babe695d3 completed April 29, 2026, 3:18 a.m.
NED1 Entity disambiguation (via context triple) batch_6a0b73fa5a648190b90ba303d1fe2397 completed May 18, 2026, 8:18 p.m.
NEDg Description generation batch_6a0b7755eb048190ba1657a9a09bc24b completed May 18, 2026, 8:32 p.m.
NED2 Entity disambiguation (via description) batch_6a0b780c0a4c8190b51b50c1e0e1a114 completed May 18, 2026, 8:35 p.m.
Created at: April 17, 2026, 3:13 p.m.