Triple

T22690298
Position Surface form Disambiguated ID Type / Status
Subject CDK4 E561032 entity
Predicate regulatedBy P86 FINISHED
Object CDKN2C (p18INK4C)
CDKN2C (p18INK4C) is a cyclin-dependent kinase inhibitor that helps control cell cycle progression by inhibiting CDK4/6 activity and acting as a tumor suppressor.
 E1552431 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: CDKN2C (p18INK4C) | Statement: [CDK4, regulatedBy, CDKN2C (p18INK4C)]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: CDKN2C (p18INK4C)
Context triple: [CDK4, regulatedBy, CDKN2C (p18INK4C)]
  • A. CDKN2B (p15INK4B)
    CDKN2B (p15INK4B) is a cyclin-dependent kinase inhibitor tumor suppressor protein that controls cell cycle progression by inhibiting CDK4/6 activity.
  • B. CDKN2A (p16INK4A)
    CDKN2A (p16INK4A) is a tumor suppressor gene encoding a cyclin-dependent kinase inhibitor that controls cell cycle progression and is frequently inactivated in human cancers.
  • C. CDK4
    CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
  • D. CDK6
    CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
  • E. cyclin D2
    Cyclin D2 is a regulatory protein that controls progression through the G1 phase of the cell cycle by activating cyclin-dependent kinases involved in cell proliferation.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: CDKN2C (p18INK4C)
Triple: [CDK4, regulatedBy, CDKN2C (p18INK4C)]
Generated description
CDKN2C (p18INK4C) is a cyclin-dependent kinase inhibitor that helps control cell cycle progression by inhibiting CDK4/6 activity and acting as a tumor suppressor.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: CDKN2C (p18INK4C)
Target entity description: CDKN2C (p18INK4C) is a cyclin-dependent kinase inhibitor that helps control cell cycle progression by inhibiting CDK4/6 activity and acting as a tumor suppressor.
  • A. CDKN2B (p15INK4B)
    CDKN2B (p15INK4B) is a cyclin-dependent kinase inhibitor tumor suppressor protein that controls cell cycle progression by inhibiting CDK4/6 activity.
  • B. CDKN2A (p16INK4A)
    CDKN2A (p16INK4A) is a tumor suppressor gene encoding a cyclin-dependent kinase inhibitor that controls cell cycle progression and is frequently inactivated in human cancers.
  • C. CDK4
    CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
  • D. CDK6
    CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
  • E. cyclin D2
    Cyclin D2 is a regulatory protein that controls progression through the G1 phase of the cell cycle by activating cyclin-dependent kinases involved in cell proliferation.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69e2454d71b48190a1f80af9f82b6fcf completed April 17, 2026, 2:35 p.m.
NER Named-entity recognition batch_69f1789a1fd08190bce5fa0babe695d3 completed April 29, 2026, 3:18 a.m.
NED1 Entity disambiguation (via context triple) batch_6a0b8fb965fc8190830b24f0bf0e2e4d completed May 18, 2026, 10:16 p.m.
NEDg Description generation batch_6a0b93d4b8e08190a0542ffc42f12814 completed May 18, 2026, 10:33 p.m.
NED2 Entity disambiguation (via description) batch_6a0b94bbb9c88190a7ab0937d1b398a5 completed May 18, 2026, 10:37 p.m.
Created at: April 17, 2026, 3:13 p.m.