Triple

T22516271
Position Surface form Disambiguated ID Type / Status
Subject Cdc28 E556655 entity
Predicate substrate P16678 FINISHED
Object Cdh1
Cdh1 is a regulatory protein that activates the anaphase-promoting complex/cyclosome (APC/C) to control mitotic exit and G1 phase progression in the cell cycle.
 E1539823 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Cdh1 | Statement: [Cdc28, substrate, Cdh1]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: Cdh1
Context triple: [Cdc28, substrate, Cdh1]
  • A. CDK4
    CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
  • B. CDK6
    CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
  • C. c-Myc
    c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
  • D. Cdc28
    Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
  • E. TARDBP
    TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Cdh1
Triple: [Cdc28, substrate, Cdh1]
Generated description
Cdh1 is a regulatory protein that activates the anaphase-promoting complex/cyclosome (APC/C) to control mitotic exit and G1 phase progression in the cell cycle.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: Cdh1
Target entity description: Cdh1 is a regulatory protein that activates the anaphase-promoting complex/cyclosome (APC/C) to control mitotic exit and G1 phase progression in the cell cycle.
  • A. CDK4
    CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
  • B. CDK6
    CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
  • C. c-Myc
    c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
  • D. Cdc28
    Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
  • E. TARDBP
    TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69e11e5657e881909f16ca58352c50da completed April 16, 2026, 5:37 p.m.
NER Named-entity recognition batch_69f15e2cfc908190b3489228a1997f45 completed April 29, 2026, 1:26 a.m.
NED1 Entity disambiguation (via context triple) batch_6a0b17f152848190b4c8dc77596d625d completed May 18, 2026, 1:45 p.m.
NEDg Description generation batch_6a0b1842c7208190801bce8d6fdb2bca completed May 18, 2026, 1:46 p.m.
NED2 Entity disambiguation (via description) batch_6a0b1910f4a8819081644157406c523f completed May 18, 2026, 1:50 p.m.
Created at: April 16, 2026, 8:50 p.m.