Triple

T19992750
Position Surface form Disambiguated ID Type / Status
Subject Exelon Patch E494103 entity
Predicate regulatesEnzyme P51774 FINISHED
Object butyrylcholinesterase
Butyrylcholinesterase is a human enzyme that hydrolyzes choline-based esters and plays a role in drug metabolism and modulation of cholinergic neurotransmission.
 E1405307 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: butyrylcholinesterase | Statement: [Exelon Patch, regulatesEnzyme, butyrylcholinesterase]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: butyrylcholinesterase
Context triple: [Exelon Patch, regulatesEnzyme, butyrylcholinesterase]
  • A. catechol-O-methyltransferase
    Catechol-O-methyltransferase is an enzyme that inactivates catecholamine neurotransmitters and related drugs by transferring a methyl group to their catechol structures.
  • B. ase
    "ase" is the ISO 639-3 language code assigned to American Sign Language, the primary sign language used by Deaf communities in the United States and parts of Canada.
  • C. Activase
    Activase is a brand-name form of the clot-dissolving drug alteplase, widely used as a thrombolytic treatment for acute ischemic stroke and certain types of heart attack and pulmonary embolism.
  • D. Chelechol
    Chelechol is a small village located within Aimeliik State in the island nation of Palau.
  • E. M2 muscarinic acetylcholine receptor
    The M2 muscarinic acetylcholine receptor is a G protein–coupled receptor subtype primarily found in the heart, where it mediates parasympathetic (vagal) effects such as slowing heart rate and reducing contractility.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: butyrylcholinesterase
Triple: [Exelon Patch, regulatesEnzyme, butyrylcholinesterase]
Generated description
Butyrylcholinesterase is a human enzyme that hydrolyzes choline-based esters and plays a role in drug metabolism and modulation of cholinergic neurotransmission.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: butyrylcholinesterase
Target entity description: Butyrylcholinesterase is a human enzyme that hydrolyzes choline-based esters and plays a role in drug metabolism and modulation of cholinergic neurotransmission.
  • A. catechol-O-methyltransferase
    Catechol-O-methyltransferase is an enzyme that inactivates catecholamine neurotransmitters and related drugs by transferring a methyl group to their catechol structures.
  • B. ase
    "ase" is the ISO 639-3 language code assigned to American Sign Language, the primary sign language used by Deaf communities in the United States and parts of Canada.
  • C. Activase
    Activase is a brand-name form of the clot-dissolving drug alteplase, widely used as a thrombolytic treatment for acute ischemic stroke and certain types of heart attack and pulmonary embolism.
  • D. Chelechol
    Chelechol is a small village located within Aimeliik State in the island nation of Palau.
  • E. M2 muscarinic acetylcholine receptor
    The M2 muscarinic acetylcholine receptor is a G protein–coupled receptor subtype primarily found in the heart, where it mediates parasympathetic (vagal) effects such as slowing heart rate and reducing contractility.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69da626a67648190af9653832a3aeced completed April 11, 2026, 3:02 p.m.
NER Named-entity recognition batch_69e65fe10ffc81908c94168b0a8ea9c9 completed April 20, 2026, 5:18 p.m.
NED1 Entity disambiguation (via context triple) batch_6a080503f1bc8190b71f6d7043ac6593 completed May 16, 2026, 5:47 a.m.
NEDg Description generation batch_6a0806563e1c8190b702fcfc009c84d5 completed May 16, 2026, 5:53 a.m.
NED2 Entity disambiguation (via description) batch_6a0806e876c881909f0c30e5dd16ce20 completed May 16, 2026, 5:55 a.m.
Created at: April 11, 2026, 3:31 p.m.