Peyer’s patches
E902888
Peyer’s patches are organized lymphoid nodules in the small intestine that play a key role in gut-associated immune responses, particularly in generating antibody-producing B cells.
All labels observed (3)
| Label | Occurrences |
|---|---|
| Peyer patches | 1 |
| Peyer’s patches canonical | 1 |
| gut-associated lymphoid tissue | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T11074456 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Peyer’s patches Context triple: [B lymphocytes, foundIn, Peyer’s patches]
-
A.
Spleen
"Spleen" is a famous melancholic poem by Charles Baudelaire from his collection *Les Fleurs du mal*, exploring themes of ennui, despair, and existential anguish.
-
B.
Lancre
Lancre is a small, mountainous kingdom in Terry Pratchett’s Discworld series, best known as the home of the witches Granny Weatherwax, Nanny Ogg, and Magrat Garlick.
-
C.
Jacobson’s organ
Jacobson’s organ, also known as the vomeronasal organ, is a chemosensory structure in many vertebrates that detects pheromones and other chemical cues to aid in behaviors like hunting, mating, and social communication.
-
D.
Periton
Periton is a residential area and suburb on the outskirts of Minehead in Somerset, England.
-
E.
Bilein
Bilein is an alternative name for the Bilen people, an ethnic group primarily inhabiting parts of Eritrea and eastern Sudan.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Peyer’s patches Target entity description: Peyer’s patches are organized lymphoid nodules in the small intestine that play a key role in gut-associated immune responses, particularly in generating antibody-producing B cells.
-
A.
Spleen
"Spleen" is a famous melancholic poem by Charles Baudelaire from his collection *Les Fleurs du mal*, exploring themes of ennui, despair, and existential anguish.
-
B.
Lancre
Lancre is a small, mountainous kingdom in Terry Pratchett’s Discworld series, best known as the home of the witches Granny Weatherwax, Nanny Ogg, and Magrat Garlick.
-
C.
Jacobson’s organ
Jacobson’s organ, also known as the vomeronasal organ, is a chemosensory structure in many vertebrates that detects pheromones and other chemical cues to aid in behaviors like hunting, mating, and social communication.
-
D.
Periton
Periton is a residential area and suburb on the outskirts of Minehead in Somerset, England.
-
E.
Bilein
Bilein is an alternative name for the Bilen people, an ethnic group primarily inhabiting parts of Eritrea and eastern Sudan.
- F. None of above. chosen
Statements (46)
| Predicate | Object |
|---|---|
| instanceOf |
gut-associated lymphoid tissue
ⓘ
lymphoid nodule ⓘ secondary lymphoid organ ⓘ |
| antigenUptakeMediatedBy | M cells ⓘ |
| arrangedAlong | antimesenteric border of small intestine ⓘ |
| associatedWith |
mucosal homing of lymphocytes
ⓘ
secretory IgA production ⓘ |
| containsCellType |
B lymphocyte
ⓘ
M cell ⓘ T lymphocyte ⓘ dendritic cell ⓘ follicular dendritic cell ⓘ macrophage ⓘ |
| containsStructure |
B cell follicle
ⓘ
T cell–rich interfollicular area ⓘ germinal center ⓘ subepithelial dome ⓘ |
| coveredBy | follicle-associated epithelium ⓘ |
| developsPredominantly | in early life ⓘ |
| discoveredBy | Johann Conrad Peyer ⓘ |
| drainsTo | mesenteric lymph nodes ⓘ |
| foundInLayer |
lamina propria
ⓘ
submucosa ⓘ |
| function |
defense against enteric pathogens
ⓘ
development of oral tolerance ⓘ generation of antibody-producing B cells ⓘ induction of IgA class switching ⓘ initiation of mucosal immune responses ⓘ sampling of luminal antigens ⓘ |
| hasEpitheliumType | specialized follicle-associated epithelium lacking typical villi ⓘ |
| hasHighEndothelialVenules | true ⓘ |
| locatedIn | small intestine ⓘ |
| locatedPrimarilyIn | ileum ⓘ |
| macroscopicAppearance | oval or elongated lymphoid aggregates ⓘ |
| moreNumerousIn | children ⓘ |
| namedAfter | Johann Conrad Peyer ⓘ |
| numberVariesBetween | individuals ⓘ |
| partOf |
gut-associated immune system
ⓘ
immune system ⓘ mucosa-associated lymphoid tissue ⓘ |
| roleInDisease |
entry site for some enteric pathogens
ⓘ
involved in pathogenesis of inflammatory bowel disease ⓘ |
| roleInVaccineResponse | target for oral vaccines ⓘ |
| species |
present in humans
ⓘ
present in many mammals ⓘ |
| undergoes | age-related involution ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Peyer’s patches Description of subject: Peyer’s patches are organized lymphoid nodules in the small intestine that play a key role in gut-associated immune responses, particularly in generating antibody-producing B cells.
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: Peyer’s patches
linked to: Peyer’s patches