ScaleA2
E902751
ScaleA2 is an improved variant of the Scale tissue clearing method designed to render biological tissues more transparent while better preserving fluorescent signals for high-resolution imaging.
All labels observed (1)
| Label | Occurrences |
|---|---|
| ScaleA2 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T11057944 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: ScaleA2 Context triple: [Scale tissue clearing method, notableVariant, ScaleA2]
-
A.
Skala
Skala is the main port town and one of the primary settlements on the Greek island of Patmos, known for its harbor, waterfront promenade, and role as the island’s commercial and transportation hub.
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B.
Skala
Skala is a surname most notably associated with Austrian-American actress and architect Lilia Skala.
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C.
Skala
Skala is a coastal village and popular tourist resort located on the southeastern tip of the Greek island of Kefalonia.
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D.
North Scale
North Scale is a small village on Walney Island in Cumbria, England, known historically as a fishing community and now as a residential suburb of Barrow-in-Furness.
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E.
Schaal
Schaal is a surname most notably associated with American actress Wendy Schaal, known for her work in film and television voice acting.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: ScaleA2 Target entity description: ScaleA2 is an improved variant of the Scale tissue clearing method designed to render biological tissues more transparent while better preserving fluorescent signals for high-resolution imaging.
-
A.
Skala
Skala is the main port town and one of the primary settlements on the Greek island of Patmos, known for its harbor, waterfront promenade, and role as the island’s commercial and transportation hub.
-
B.
Skala
Skala is a surname most notably associated with Austrian-American actress and architect Lilia Skala.
-
C.
Skala
Skala is a coastal village and popular tourist resort located on the southeastern tip of the Greek island of Kefalonia.
-
D.
North Scale
North Scale is a small village on Walney Island in Cumbria, England, known historically as a fishing community and now as a residential suburb of Barrow-in-Furness.
-
E.
Schaal
Schaal is a surname most notably associated with American actress Wendy Schaal, known for her work in film and television voice acting.
- F. None of above. chosen
Statements (45)
| Predicate | Object |
|---|---|
| instanceOf |
biological sample preparation method
ⓘ
tissue clearing reagent ⓘ tissue clearing solution ⓘ |
| aimsToMaintain | fluorescence intensity over long imaging times ⓘ |
| aimsToReduce | light scattering in tissues ⓘ |
| appliedTo |
brain tissue
ⓘ
neural tissue ⓘ other organ tissues ⓘ |
| compatibleWith |
fluorescent dyes
ⓘ
fluorescent proteins ⓘ |
| designedFor | biological tissues ⓘ |
| developedFor | clearing of fixed tissues ⓘ |
| developedInContextOf | whole‑brain imaging techniques ⓘ |
| enables |
deep tissue imaging
ⓘ
visualization of fine cellular structures ⓘ |
| hasAdvantage | better fluorescence signal preservation than ScaleA ⓘ |
| hasAdvantageOver | ScaleA ⓘ |
| hasComponent |
Triton X‑100
ⓘ
glycerol ⓘ urea ⓘ |
| hasProperty |
aqueous solution
ⓘ
compatible with high‑resolution imaging ⓘ high tissue transparency ⓘ improved fluorescence preservation ⓘ |
| hasPurpose |
enable high‑resolution imaging
ⓘ
preserve fluorescent signals ⓘ render biological tissues more transparent ⓘ tissue clearing ⓘ |
| improvesUpon | Scale ⓘ |
| isDocumentedIn | peer‑reviewed scientific literature ⓘ |
| isPartOf | Scale tissue clearing method family ⓘ |
| isUsedIn |
developmental biology research
ⓘ
histology and pathology research ⓘ neuroscience research ⓘ |
| isVariantOf | Scale ⓘ |
| operatesAt | room temperature or slightly elevated temperature ⓘ |
| precedes |
more recent tissue clearing methods such as CLARITY
ⓘ
more recent tissue clearing methods such as CUBIC ⓘ more recent tissue clearing methods such as SeeDB ⓘ |
| relatedTo |
ScaleB
ⓘ
ScaleU2 ⓘ |
| requires | incubation of tissue samples ⓘ |
| usedFor |
fluorescence microscopy
ⓘ
optical imaging of thick tissues ⓘ three‑dimensional imaging of tissues ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: ScaleA2 Description of subject: ScaleA2 is an improved variant of the Scale tissue clearing method designed to render biological tissues more transparent while better preserving fluorescent signals for high-resolution imaging.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.