dentate gyrus

E874320

The dentate gyrus is a subregion of the hippocampal formation crucial for forming new episodic memories and supporting adult neurogenesis.

All labels observed (1)

Label Occurrences
dentate gyrus canonical 2

How this entity was disambiguated

Statements (49)

Predicate Object
instanceOf brain region ⓘ
hippocampal subregion ⓘ
adultNeurogenesisOccursIn subgranular zone ⓘ
associatedWith Alzheimer's disease ⓘ
major depressive disorder ⓘ
temporal lobe epilepsy ⓘ
containsCellType GABAergic interneuron ⓘ
granule cell ⓘ
mossy cell ⓘ
neural progenitor cell ⓘ
neural stem cell ⓘ
containsRegion subgranular zone ⓘ
discoveredBy Santiago Ramón y Cajal ⓘ
hasFunction discrimination of similar contexts ⓘ
filtering of entorhinal input ⓘ
orthogonalization of input patterns ⓘ
regulation of hippocampal excitability ⓘ
sparse coding of cortical inputs ⓘ
hasHighExpressionOf doublecortin in immature neurons ⓘ
progranule cell markers ⓘ
hasLayer granule cell layer ⓘ
inner molecular layer ⓘ
middle molecular layer ⓘ
outer molecular layer ⓘ
polymorphic layer ⓘ
hasSubregion granule cell layer of dentate gyrus ⓘ
hilus of dentate gyrus ⓘ
molecular layer of dentate gyrus ⓘ
involvedIn adult neurogenesis ⓘ
cognitive flexibility ⓘ
contextual fear conditioning ⓘ
episodic memory formation ⓘ
pattern separation ⓘ
spatial memory ⓘ
locatedIn limbic system ⓘ
linked to: Limbic system

medial temporal lobe ⓘ
partOf hippocampal formation ⓘ
linked to: hippocampus

hippocampus ⓘ
projectsTo CA3 region of hippocampus ⓘ
projectsVia mossy fibers ⓘ
receivesInputFrom entorhinal cortex ⓘ
receivesInputVia perforant path ⓘ
species present in mammals ⓘ
supportsProcess adult hippocampal neurogenesis ⓘ
synonym dentate area ⓘ
fascia dentata ⓘ
vulnerableTo aging-related decline ⓘ
seizure-induced reorganization ⓘ
stress-induced changes ⓘ

How these facts were elicited

Referenced by (2)

Full triples — surface form annotated when it differs from this entity's canonical label.

hippocampus → hasPart → dentate gyrus ⓘ
entorhinal cortex → connectsTo → dentate gyrus ⓘ