Molecular Evolutionary Clock
E612271
Molecular Evolutionary Clock is a foundational concept in evolutionary biology that uses the rate of genetic mutations to estimate the timing of species divergence and evolutionary events.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Molecular Evolutionary Clock canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T6683329 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Molecular Evolutionary Clock Context triple: [Motoo Kimura, notableWork, Molecular Evolutionary Clock]
-
A.
Motoo Kimura's neutral theory of molecular evolution
Motoo Kimura's neutral theory of molecular evolution is a foundational concept in evolutionary biology proposing that most genetic variation and molecular changes are selectively neutral and shaped primarily by random genetic drift rather than natural selection.
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B.
Genetics of the Evolutionary Process
Genetics of the Evolutionary Process is a seminal work in evolutionary biology that synthesizes genetic principles with natural selection to explain how evolutionary change occurs within and between populations.
-
C.
The Causes of Evolution
The Causes of Evolution is a foundational 1932 book by geneticist J. B. S. Haldane that helped establish the modern synthesis by mathematically integrating Mendelian genetics with Darwinian natural selection.
-
D.
Evolution in Mendelian Populations
"Evolution in Mendelian Populations" is a foundational 1931 paper by Sewall Wright that introduced key concepts of population genetics, including genetic drift, inbreeding, and the shifting balance theory of evolution.
-
E.
Evolution: The Modern Synthesis
Evolution: The Modern Synthesis is Julian Huxley’s influential 1942 book that helped popularize and articulate the unified, gene-centered framework of modern evolutionary theory.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Molecular Evolutionary Clock Target entity description: Molecular Evolutionary Clock is a foundational concept in evolutionary biology that uses the rate of genetic mutations to estimate the timing of species divergence and evolutionary events.
-
A.
Motoo Kimura's neutral theory of molecular evolution
Motoo Kimura's neutral theory of molecular evolution is a foundational concept in evolutionary biology proposing that most genetic variation and molecular changes are selectively neutral and shaped primarily by random genetic drift rather than natural selection.
-
B.
Genetics of the Evolutionary Process
Genetics of the Evolutionary Process is a seminal work in evolutionary biology that synthesizes genetic principles with natural selection to explain how evolutionary change occurs within and between populations.
-
C.
The Causes of Evolution
The Causes of Evolution is a foundational 1932 book by geneticist J. B. S. Haldane that helped establish the modern synthesis by mathematically integrating Mendelian genetics with Darwinian natural selection.
-
D.
Evolution in Mendelian Populations
"Evolution in Mendelian Populations" is a foundational 1931 paper by Sewall Wright that introduced key concepts of population genetics, including genetic drift, inbreeding, and the shifting balance theory of evolution.
-
E.
Evolution: The Modern Synthesis
Evolution: The Modern Synthesis is Julian Huxley’s influential 1942 book that helped popularize and articulate the unified, gene-centered framework of modern evolutionary theory.
- F. None of above. chosen
Statements (49)
| Predicate | Object |
|---|---|
| instanceOf |
concept in evolutionary biology
ⓘ
dating technique in biology ⓘ method in molecular evolution ⓘ |
| aimsTo |
estimate timing of evolutionary events
ⓘ
estimate timing of species divergence ⓘ |
| appliedIn |
studies of biodiversity and speciation
ⓘ
studies of human evolution ⓘ studies of viral evolution ⓘ |
| appliesTo |
genes
ⓘ
genomes ⓘ proteins ⓘ |
| assumes |
lineages diverge at measurable molecular rates
ⓘ
mutations accumulate over time ⓘ |
| basedOn |
assumption of approximately constant mutation rate
ⓘ
molecular sequence comparisons ⓘ |
| calibratedWith |
biogeographic events
ⓘ
fossil record ⓘ known historical divergence times ⓘ |
| contrastsWith | morphological dating alone ⓘ |
| developedInContextOf | molecular evolution theory ⓘ |
| field |
evolutionary biology
ⓘ
molecular evolution ⓘ |
| hasVariant |
local molecular clock
ⓘ
relaxed molecular clock ⓘ strict molecular clock ⓘ |
| helpsExplain | tempo of molecular evolution ⓘ |
| helpsIntegrate | molecular data with fossil data ⓘ |
| influencedBy |
generation time
ⓘ
mutation rate variation among lineages ⓘ population size ⓘ selection pressures ⓘ |
| modeledBy |
Bayesian methods
ⓘ
maximum likelihood methods ⓘ |
| relatedTo |
comparative genomics
ⓘ
divergence time estimation ⓘ molecular phylogeny ⓘ phylogenetic trees ⓘ phylogenetics ⓘ |
| requires |
sequence alignment
ⓘ
substitution models ⓘ |
| supports | reconstruction of evolutionary timelines ⓘ |
| usedFor |
dating lineage splits
ⓘ
dating speciation events ⓘ estimating time to most recent common ancestor ⓘ testing evolutionary hypotheses ⓘ |
| uses |
DNA sequence data
ⓘ
nucleotide substitution rates ⓘ protein sequence data ⓘ rate of genetic mutations ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Molecular Evolutionary Clock Description of subject: Molecular Evolutionary Clock is a foundational concept in evolutionary biology that uses the rate of genetic mutations to estimate the timing of species divergence and evolutionary events.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.