Purkinje fibers

E431116

Purkinje fibers are specialized cardiac muscle fibers that rapidly conduct electrical impulses through the ventricles, coordinating their synchronized contraction.

All labels observed (1)

Label Occurrences
Purkinje fibers canonical 1

How this entity was disambiguated

Statements (46)

Predicate Object
instanceOf cardiac muscle fiber ⓘ
component of cardiac conduction system ⓘ
specialized conducting fiber ⓘ
associatedWith bundle branch block when conduction impaired ⓘ
ventricular arrhythmias when abnormal ⓘ
bloodSupplyFrom coronary arteries ⓘ
clinicalRelevance site of origin for some idiopathic ventricular tachycardias ⓘ
target of some antiarrhythmic drugs ⓘ
connectedTo left bundle branch ⓘ
right bundle branch ⓘ
ventricular myocardium ⓘ
developFrom cardiac muscle cells ⓘ
discoveredBy Jan Evangelista Purkyně ⓘ
discoveryYear 1839 ⓘ
electrophysiologyProperty can exhibit automaticity under pathological conditions ⓘ
fast response action potentials ⓘ
high upstroke velocity of phase 0 ⓘ
function coordination of synchronized ventricular contraction ⓘ
distribution of impulses from bundle branches to ventricular myocardium ⓘ
rapid conduction of electrical impulses in ventricles ⓘ
hasProperty abundant glycogen ⓘ
few myofibrils ⓘ
high conduction velocity ⓘ
large diameter ⓘ
pale cytoplasm ⓘ
poor contractile function ⓘ
rich in gap junctions ⓘ
specialized for impulse conduction rather than contraction ⓘ
histologyFeature larger than surrounding ventricular myocytes ⓘ
located beneath endocardium ⓘ
myofibrils concentrated at periphery of cell ⓘ
innervatedBy autonomic nervous system indirectly via myocardium ⓘ
locatedIn left ventricle ⓘ
right ventricle ⓘ
subendocardial region of ventricles ⓘ
namedAfter Jan Evangelista Purkyně ⓘ
partOf heart ⓘ
ventricular conduction system ⓘ
receivesImpulseFrom atrioventricular bundle ⓘ
bundle branches ⓘ
roleIn QRS complex of electrocardiogram ⓘ
synchronous ventricular depolarization ⓘ
speciesPresentIn humans ⓘ
mammals ⓘ
stainCharacteristic PAS positive due to glycogen ⓘ
transmitsImpulseTo ventricular muscle cells ⓘ

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

Heart → hasPart → Purkinje fibers ⓘ