Ervebo

E414773

Ervebo is a recombinant, live-attenuated vaccine developed to protect humans against infection by the Zaire ebolavirus.

All labels observed (1)

Label Occurrences
Ervebo canonical 2

How this entity was disambiguated

Statements (51)

Predicate Object
instanceOf Ebola vaccine ⓘ
live-attenuated vaccine ⓘ
recombinant vaccine ⓘ
vaccine ⓘ
hasAdministrationSchedule single-dose regimen ⓘ
hasAdministrationSite deltoid muscle ⓘ
hasATCCode J07BX02 ⓘ
hasClinicalTrialPhase Phase 3 completed ⓘ
hasCommonAdverseEffect arthralgia ⓘ
fatigue ⓘ
fever ⓘ
headache ⓘ
injection site pain ⓘ
injection site swelling ⓘ
myalgia ⓘ
hasComponent Zaire ebolavirus glycoprotein ⓘ
vesicular stomatitis virus glycoprotein G deletion ⓘ
hasDeveloper Merck & Co. ⓘ
NewLink Genetics ⓘ
Public Health Agency of Canada ⓘ
hasDosageForm suspension for injection ⓘ
hasEfficacy high efficacy against Zaire ebolavirus in clinical trials ⓘ
hasGenericName rVSV-ZEBOV ⓘ
rVSVΔG-ZEBOV-GP ⓘ
linked to: rVSV-ZEBOV
hasIndication pre-exposure prophylaxis against Ebola virus disease caused by Zaire ebolavirus ⓘ
protection of individuals at high risk of exposure to Zaire ebolavirus ⓘ
hasMarketingAuthorizationHolder Merck Sharp & Dohme Corp. ⓘ
linked to: Merck & Co.
hasRegulatoryApproval European Commission ⓘ
Health Canada ⓘ
U.S. Food and Drug Administration ⓘ
World Health Organization prequalification ⓘ
multiple African national regulatory authorities ⓘ
hasRouteOfAdministration intramuscular injection ⓘ
hasStorageRequirement frozen storage ⓘ
hasStorageTemperature -60°C to -80°C (original formulation) ⓘ
hasViralVector recombinant vesicular stomatitis virus ⓘ
hasWHOClassification Ebola Zaire vaccine ⓘ
isAttenuated true ⓘ
isIndicatedForAgeGroup 18 years and older ⓘ
isLive true ⓘ
isRecombinant true ⓘ
isReplicationCompetent true ⓘ
isUsedInOutbreakResponse true ⓘ
targetsDisease Ebola virus disease ⓘ
targetsVirus Zaire ebolavirus ⓘ
wasApprovedInEUOn 2019-11-11 ⓘ
wasApprovedInUSOn 2019-12-19 ⓘ
wasInitiallyDevelopedBy Public Health Agency of Canada ⓘ
wasPrequalifiedByWHOIn 2019 ⓘ
wasUsedInOutbreak 2014–2016 West Africa Ebola outbreak ⓘ
2018–2020 Ebola outbreak in the Democratic Republic of the Congo ⓘ

How these facts were elicited

Referenced by (2)

Full triples — surface form annotated when it differs from this entity's canonical label.

rVSV-ZEBOV → alsoKnownAs → Ervebo ⓘ