Haldane’s dilemma
E194835
Haldane’s dilemma is a theoretical argument in population genetics that questions how rapidly beneficial genetic substitutions can accumulate in a population given the reproductive cost of natural selection.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Haldane’s dilemma canonical | 2 |
How this entity was disambiguated
This entity first appeared as the object of triple T1726033 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Haldane’s dilemma Context triple: [J. B. S. Haldane, notableFor, Haldane’s dilemma]
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A.
Hardy–Weinberg principle
The Hardy–Weinberg principle is a fundamental concept in population genetics that describes how allele and genotype frequencies remain constant from generation to generation in an idealized, non-evolving population.
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B.
Genetics and the Origin of Species
Genetics and the Origin of Species is a 1937 book by Theodosius Dobzhansky that helped found the modern evolutionary synthesis by integrating Mendelian genetics with Darwinian natural selection.
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C.
Essays of a Biologist
Essays of a Biologist is a collection of influential essays by evolutionary biologist Julian Huxley that explores biology’s implications for human society, philosophy, and the modern worldview.
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D.
Evolution: The Modern Synthesis
Evolution: The Modern Synthesis is Julian Huxley’s influential 1942 book that helped popularize and articulate the unified, gene-centered framework of modern evolutionary theory.
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E.
Acquiring Genomes: A Theory of the Origins of Species
Acquiring Genomes: A Theory of the Origins of Species is a scientific book by Lynn Margulis that advances the idea that symbiosis and the merging of genomes are central drivers of evolutionary innovation and the formation of new species.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Haldane’s dilemma Target entity description: Haldane’s dilemma is a theoretical argument in population genetics that questions how rapidly beneficial genetic substitutions can accumulate in a population given the reproductive cost of natural selection.
-
A.
Hardy–Weinberg principle
The Hardy–Weinberg principle is a fundamental concept in population genetics that describes how allele and genotype frequencies remain constant from generation to generation in an idealized, non-evolving population.
-
B.
Genetics and the Origin of Species
Genetics and the Origin of Species is a 1937 book by Theodosius Dobzhansky that helped found the modern evolutionary synthesis by integrating Mendelian genetics with Darwinian natural selection.
-
C.
Essays of a Biologist
Essays of a Biologist is a collection of influential essays by evolutionary biologist Julian Huxley that explores biology’s implications for human society, philosophy, and the modern worldview.
-
D.
Evolution: The Modern Synthesis
Evolution: The Modern Synthesis is Julian Huxley’s influential 1942 book that helped popularize and articulate the unified, gene-centered framework of modern evolutionary theory.
-
E.
Acquiring Genomes: A Theory of the Origins of Species
Acquiring Genomes: A Theory of the Origins of Species is a scientific book by Lynn Margulis that advances the idea that symbiosis and the merging of genomes are central drivers of evolutionary innovation and the formation of new species.
- F. None of above. chosen
Statements (42)
| Predicate | Object |
|---|---|
| instanceOf |
concept in evolutionary biology
ⓘ
theoretical argument in population genetics ⓘ |
| addresses | how rapidly beneficial genetic substitutions can accumulate ⓘ |
| assumes |
finite reproductive excess in populations
ⓘ
selection has a reproductive cost ⓘ |
| basedOn |
cost of selection per substitution
ⓘ
time required for allele fixation ⓘ |
| concerns |
cost of natural selection
ⓘ
genetic load ⓘ rate of substitution of beneficial alleles ⓘ speed of adaptive evolution ⓘ |
| field |
evolutionary biology
ⓘ
population genetics ⓘ |
| hasBeenAddressedBy |
Motoo Kimura’s work on neutral substitutions
ⓘ
background selection and linkage models ⓘ models of soft selection ⓘ neutral theory of molecular evolution ⓘ polygenic adaptation models ⓘ |
| hasInfluenceOn |
creation–evolution controversy discussions
ⓘ
debates about feasibility of rapid evolution ⓘ |
| hasInterpretation | constraint on cumulative selective cost over time ⓘ |
| implies |
trade-off between selection intensity and reproductive output
ⓘ
upper bound on rate of adaptive substitutions ⓘ |
| introducedBy | J. B. S. Haldane ⓘ |
| involvesAssumption |
hard selection
ⓘ
independent substitutions ⓘ |
| involvesConcept |
effective population size
ⓘ
generation time ⓘ selective deaths ⓘ substitutional load ⓘ |
| mathematicallyAnalyzes |
number of selective deaths per substitution
ⓘ
time scale of allele frequency change under selection ⓘ |
| namedAfter | J. B. S. Haldane ⓘ |
| publicationContext | mid-20th century population genetics literature ⓘ |
| relatedConcept |
Haldane’s cost of selection
ⓘ
adaptive evolution in large populations ⓘ genetic load theory ⓘ substitution rate ⓘ |
| relatesTo |
fixation of advantageous mutations
ⓘ
substitution rate limits under selection ⓘ |
| usedInArgument |
constraints on macroevolutionary change
ⓘ
limits on speed of human evolution ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Haldane’s dilemma Description of subject: Haldane’s dilemma is a theoretical argument in population genetics that questions how rapidly beneficial genetic substitutions can accumulate in a population given the reproductive cost of natural selection.
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.