TFIIH
E1552443
UNEXPLORED
TFIIH is a multi-subunit protein complex essential for transcription initiation by RNA polymerase II and for nucleotide excision DNA repair.
All labels observed (1)
| Label | Occurrences |
|---|---|
| TFIIH canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22693408 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: TFIIH Context triple: [RNA polymerase II, interactsWith, TFIIH]
-
A.
TFIID
TFIID is a multi-subunit transcription factor complex that recognizes core promoter elements and helps recruit RNA polymerase II to initiate gene transcription in eukaryotic cells.
-
B.
TFIIE
TFIIE is a general transcription factor that helps recruit and regulate RNA polymerase II during the initiation of eukaryotic gene transcription.
-
C.
TFIIB
TFIIB is a general transcription factor that helps recruit and position RNA polymerase II at gene promoters to initiate transcription in eukaryotic cells.
-
D.
TFIIF
TFIIF is a general transcription factor that associates with RNA polymerase II to facilitate transcription initiation and elongation in eukaryotic cells.
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E.
Pol II
Pol II is the eukaryotic RNA polymerase enzyme complex responsible for transcribing protein-coding genes into messenger RNA.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: TFIIH Target entity description: TFIIH is a multi-subunit protein complex essential for transcription initiation by RNA polymerase II and for nucleotide excision DNA repair.
-
A.
TFIID
TFIID is a multi-subunit transcription factor complex that recognizes core promoter elements and helps recruit RNA polymerase II to initiate gene transcription in eukaryotic cells.
-
B.
TFIIE
TFIIE is a general transcription factor that helps recruit and regulate RNA polymerase II during the initiation of eukaryotic gene transcription.
-
C.
TFIIB
TFIIB is a general transcription factor that helps recruit and position RNA polymerase II at gene promoters to initiate transcription in eukaryotic cells.
-
D.
TFIIF
TFIIF is a general transcription factor that associates with RNA polymerase II to facilitate transcription initiation and elongation in eukaryotic cells.
-
E.
Pol II
Pol II is the eukaryotic RNA polymerase enzyme complex responsible for transcribing protein-coding genes into messenger RNA.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.