Cdc25 homolog Mih1
E1539821
UNEXPLORED
Cdc25 homolog Mih1 is a yeast phosphatase that activates the cyclin-dependent kinase Cdc28 to promote entry into mitosis by removing inhibitory phosphorylations.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Cdc25 homolog Mih1 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22516267 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Cdc25 homolog Mih1 Context triple: [Cdc28, regulatedBy, Cdc25 homolog Mih1]
-
A.
Cdc28
Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
-
B.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
-
C.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
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D.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
E.
Schizosaccharomyces pombe
Schizosaccharomyces pombe is a species of fission yeast widely used as a model organism in molecular and cell biology, particularly for studying the cell cycle and chromosome dynamics.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Cdc25 homolog Mih1 Target entity description: Cdc25 homolog Mih1 is a yeast phosphatase that activates the cyclin-dependent kinase Cdc28 to promote entry into mitosis by removing inhibitory phosphorylations.
-
A.
Cdc28
Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
-
B.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
-
C.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
D.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
E.
Schizosaccharomyces pombe
Schizosaccharomyces pombe is a species of fission yeast widely used as a model organism in molecular and cell biology, particularly for studying the cell cycle and chromosome dynamics.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.